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Gene · 5891

MOK: MOK protein kinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MOK: MOK protein kinase. Genes, record 5891. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5891

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Gene

Symbol
MOK
HGNC
Name
MOK protein kinase
HGNC
NCBI Gene ID
5891
NCBI Gene
HGNC ID
HGNC:9833
HGNC
Ensembl
ENSG00000080823
NCBI Gene
Aliases
RAGE, RAGE-1, RAGE1, STK30
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9UQ07MAPK/MAK/MRK overlapping kinase4190Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454032Q9UQ07Espacenet
EP 4487869 A22025-01-08422Q9UQ07Espacenet
KR 1020240027895 A2024-03-04610Q9UQ07Espacenet
JP 2023036863 A2023-03-14610Q9UQ07Espacenet
JP 2022147356 A2022-10-06253Q9UQ07Espacenet
US 11446398 B22022-09-2052777Q9UQ07Espacenet
JP 2022524081 A2022-04-27155748Q9UQ07Espacenet
US 11078247 B22021-08-036914Q9UQ07Espacenet
US 10918740 B22021-02-163282Q9UQ07Espacenet
US 10869935 B22020-12-223282Q9UQ07Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants708

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMOK papersNewest fiscal year
P30CA016672Cancer Center Support Grant32025
P30CA047904Cancer Center Support Grant32025
P30CA015704Cancer Center Support Grant22025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant22025
P30CA071789University of Hawaii Cancer Center CCSG22025
P30CA118100University of New Mexico Cancer Center Support Grant22025
R35GM118182Molecular basis of bioelectronic medicine22025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)22025
ZIABC011032Post-translational modifications of Hsp9022025
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction22025

1 to 10 of 708Source NIH's project files

See all 708 nih grants

Papers1,940

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Zhenwu Decoction ameliorates experimental benign prostatic hyperplasia: association with mitochondrial quality control, oxidative stress and apoptosis regulation.J Ethnopharmacol202742521001PubTator, text miningPubMed
Combined Prognostic Value of Triglyceride-Glucose Index and Bilirubin in Drug-Eluting Stent Restenosis: From Clinical Risk Stratification to Exploratory Vascular-Cell Findings.Cardiovasc Drugs Ther202642825863PubTator, text miningPubMed
Integrated network pharmacology, molecular docking, ADMET profiling and In vitro α-amylase inhibitory evaluation of Cardiospermum halicacabum Linn. Against diabetes mellitus.In Silico Pharmacol202642798543PubTator, text miningPubMed
Timosaponin AⅢ and Gefitinib Synergistically Inhibit NSCLC by Targeting RAGE/AKT/NF-κB/VEGF Pathway.Curr Cancer Drug Targets202642786809PubTator, text miningPubMed
Natural product therapy in diabetic kidney disease: emerging multiomics-mediated signalling pathway and molecular target.Chin Med202642778934PubTator, text miningPubMed
Targeting S100A8/A9: a molecular gateway to oral inflammation, microglial activation and neuroinflammation.Front Immunol202642707793PubTator, text miningPubMed
Integrated Strategy Combining Real-World Data Mining, Network Pharmacology, and Molecular Docking to Decipher the Mechanism of Action of a Core Herbal Combination for Menopausal Syndrome.Int J Womens Health202642670310PubTator, text miningPubMed
Mangiferin Protects Human Dermal Fibroblasts Against UVB-Induced Photoaging by Regulating RAGE/NF-κB/p38 MAPK Signaling, Cellular Senescence, and ECM Homeostasis.Curr Issues Mol Biol202642651756PubTator, text miningPubMed
New insights into multi-endpoint toxicological profiles and potential molecular mechanisms for display-related organic light-emitting/modulating materials.Ecotoxicol Environ Saf202642636667PubTator, text miningPubMed
Material Basis and Mechanisms of Action of PuRenDan in the Treatment of Type 2 Diabetes Mellitus: An Integrated Network Pharmacology and Molecular Simulation Study.Pharmaceuticals (Basel)202642515787PubTator, text miningPubMed

1 to 10 of 1,940

See all 1,940 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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