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RAG2: recombination activating 2

1 protein, 24 patents, 0 drugs, 0 trials, 4,025 NIH grants and 4,781 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRAG2HGNC
Namerecombination activating 2HGNC
NCBI Gene ID5897NCBI Gene
HGNC IDHGNC:9832HGNC
EnsemblENSG00000175097NCBI Gene
AliasesRAG-2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P55895V(D)J recombination-activating protein 25271Ensembl, GeneID, HGNCUniProt

Patents 24

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461166P55895Espacenet
EP 4641201 A22025-10-294122P55895Espacenet
JP 2025517969 A2025-06-124122P55895Espacenet
JP 2024534266 A2024-09-186P55895Espacenet
EP 4268831 A22023-11-01141P55895Espacenet
US 11716974 B22023-08-0833P55895Espacenet
US 11446398 B22022-09-2072130P55895Espacenet
US 11446398 B22022-09-2072134P55895Espacenet
JP 2022524081 A2022-04-27175101P55895Espacenet
JP 2022524081 A2022-04-27175105P55895Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4025

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01AI032524Mechanism and Regulation of V(D)J Recombination472,025NIH's project files
P30CA008748Cancer Center Support Grant452,025NIH's project files
R01AI020047Mechanisms That Control Antigen Receptor Variable Region Exon Assembly352,025NIH's project files
ZIAAI001222Characterization of the cellular and molecular bases of inborn errors of immunity352,025NIH's project files
P30CA016672Cancer Center Support Grant212,025NIH's project files
R13AI094943Annual Primary Immune Deficiency Treatment Consortium (PIDTC) Workshop and Education Day162,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award142,025NIH's project files
R01AI100874The natural killer cell response against mouse cytomegalovirus infection112,025NIH's project files
ZIADK036167Structural studies of proteins involved in DNA repair and recombination112,025NIH's project files

Papers 4781

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820686PubTator, text miningPubMed
42799887PubTator, text miningPubMed
42771195PubTator, text miningPubMed
42670307PubTator, text miningPubMed
42588651PubTator, text miningPubMed
42585842PubTator, text miningPubMed
42557824PubTator, text miningPubMed
42520792PubTator, text miningPubMed
42407746PubTator, text miningPubMed
42386939PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license