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Gene · 5898

RALA: RAS like proto-oncogene A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RALA: RAS like proto-oncogene A. Genes, record 5898. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5898

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Gene

Symbol
RALA
HGNC
Name
RAS like proto-oncogene A
HGNC
NCBI Gene ID
5898
NCBI Gene
HGNC ID
HGNC:9839
HGNC
Ensembl
ENSG00000006451
NCBI Gene
Aliases
HINCONS, RAL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11233Ras-related protein Ral-A20616Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-092P11233Espacenet
WO 2026063308 A2026-03-264P11233Espacenet
JP 2026004568 A2026-01-1469750P11233Espacenet
EP 4650780 A22025-11-1914P11233Espacenet
WO 2025183123 A2025-09-0410P11233Espacenet
JP 2025517970 A2025-06-1214P11233Espacenet
JP 2023531506 A2023-07-2433P11233Espacenet
US 11446398 B22022-09-2096985P11233Espacenet
JP 2022524081 A2022-04-27199956P11233Espacenet
US 11078247 B22021-08-039331P11233Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,792

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRALA papersNewest fiscal year
P30CA016672Cancer Center Support Grant162025
P30CA006927Comprehensive Cancer Center Program at Fox Chase152025
P30CA008748Cancer Center Support Grant132025
P30CA076292Moffitt Cancer Center Support Grant132025
P40OD010440Caenorhabditis Genetics Center72025
P30CA016086Cancer Center Support Grant62025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
ZIABC010440Protein Structure, Stability, and Amyloid Formation62025
ZIABC010441Biomolecular Recognition and Binding Mechanisms62025
P30CA012197Cancer Center Support Grant52025

1 to 10 of 1,792Source NIH's project files

See all 1,792 nih grants

Papers2,381

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A RALGEF inhibitor suppresses lung cancer stem cell development and tumorigenesis.J Biol Chem202642749263PubTator, text miningPubMed
"RAL" the LDLR to lysosomes for degradation.Life Metab202642701792PubTator, text miningPubMed
Molecular mechanisms of chronic dietary cholesterol-driven remodeling of LDLR protein fate.Yi Chuan202642608182PubTator, text miningPubMed
Development and validation of QuadraSynth ML: a novel classifier for sepsis prediction.Front Cell Infect Microbiol202642564150PubTator, text miningPubMed
Single-Cell Transcriptomic Analysis Identifies an OLFM4-Associated Gastric Cancer Cell State with Palmitoylation-Related Signatures and Altered Metabolic Activities.Biomolecules202642352346PubTator, text miningPubMed
Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover.Nature202642343138PubTator, text miningPubMed
M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex in macrophages.PLoS Pathog202642224353PubTator, text miningPubMed
Targeting the Ras-Ral Signaling Axis in Type 2 Diabetes Mellitus: A Dual-Modulation Approach to Correcting Insulin Resistance and β-Cell Dysfunction.Pharmaceuticals (Basel)202642075902PubTator, text miningPubMed
KCTD10 as a selective cancer dependency from transcription-replication conflicts (TRCs).Ageing Cancer Res Treat202642037670PubTator, text miningPubMed
Computational Approach Improves Diagnostic Performance Based on Tumor-Associated Autoantibodies in Esophageal Squamous Cell Carcinoma.Comput Struct Biotechnol J202641971943PubTator, text miningPubMed

1 to 10 of 2,381

See all 2,381 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5898

GET https://conductscience.org/api/genes/v1/5898/patents?page=2