ConductScience.org, home

Gene · 5900

RALGDS: ral guanine nucleotide dissociation stimulator

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RALGDS: ral guanine nucleotide dissociation stimulator. Genes, record 5900. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5900

On this page

Gene

Symbol
RALGDS
HGNC
Name
ral guanine nucleotide dissociation stimulator
HGNC
NCBI Gene ID
5900
NCBI Gene
HGNC ID
HGNC:9842
HGNC
Ensembl
ENSG00000160271
NCBI Gene
Aliases
RGDS, RGF, RalGEF
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q12967Ral guanine nucleotide dissociation stimulator9144Ensembl, GeneID, HGNC

Source UniProt

Patents19

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1460858Q12967Espacenet
EP 4641201 A22025-10-299319Q12967Espacenet
EP 4641202 A22025-10-295537Q12967Espacenet
JP 2025517969 A2025-06-129319Q12967Espacenet
KR 1020250017231 A2025-02-045537Q12967Espacenet
US 11446398 B22022-09-2071315Q12967Espacenet
JP 2022524081 A2022-04-27174286Q12967Espacenet
JP 2019054813 A2019-04-11241293Q12967Espacenet
JP 2017121241 A2017-07-13241293Q12967Espacenet
US 9506039 B22016-11-2925Q12967Espacenet

1 to 10 of 19

See all 19 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,464

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRALGDS papersNewest fiscal year
ZIABC010440Protein Structure, Stability, and Amyloid Formation122025
P30CA016672Cancer Center Support Grant112025
P30CA076292Moffitt Cancer Center Support Grant112025
ZIABC010441Biomolecular Recognition and Binding Mechanisms112025
P20GM103446Delaware INBRE72025
P30CA006927Comprehensive Cancer Center Program at Fox Chase62025
P30CA008748Cancer Center Support Grant62025
ZIABC010442Method Development: Efficient Computer Vision Based Algorithms62025
P30CA016086Cancer Center Support Grant52025
P40OD010440Caenorhabditis Genetics Center52025

1 to 10 of 1,464Source NIH's project files

See all 1,464 nih grants

Papers1,907

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A RALGEF inhibitor suppresses lung cancer stem cell development and tumorigenesis.J Biol Chem202642749263PubTator, text miningPubMed
Tissue-Engineered Brain-Mimetic Niches to Model Braintropic Triple-Negative Breast Cancer Metastasis.Tissue Eng Part C Methods202642175838PubTator, text miningPubMed
High yield production of C-terminally processed KRAS4a, HRAS, and NRAS for biophysical study.Protein Expr Purif202642142681PubTator, text miningPubMed
Revisiting RAS family GTPase signaling: effector selectivity and oncogenic bypass.Biochem J202642017331PubTator, text miningPubMed
Systematic and precise interventions for KRAS-mutant cancers.Exp Hematol Oncol202641827015PubTator, text miningPubMed
Development and Evaluation of Benzofuran Oxoacetic Acid Compounds as EPAC1 Activators.J Med Chem202641826280PubTator, text miningPubMed
Fibronectin 1 (FN1)-rearranged Mesenchymal Neoplasms: An Updated Review.Cancer Genomics Proteomics202641771581PubTator, text miningPubMed
Phase II Trial of Vemurafenib and Sorafenib Combination in Advanced KRAS-Mutated Metastatic Pancreatic Cancer.J Immunother Precis Oncol202641766762PubTator, text miningPubMed
Matching heterogeneous cohorts by projected principal components reveals two novel Alzheimer's disease-associated genes in the Hispanic population.Alzheimers Dement202641755704PubTator, text miningPubMed
β-Hairpin-Based Peptide Hydrogels: The Case of MAX1.Gels202641744972PubTator, text miningPubMed

1 to 10 of 1,907

See all 1,907 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5900

GET https://conductscience.org/api/genes/v1/5900/patents