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Gene · 5903

RANBP2: RAN binding protein 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RANBP2: RAN binding protein 2. Genes, record 5903. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5903

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Gene

Symbol
RANBP2
HGNC
Name
RAN binding protein 2
HGNC
NCBI Gene ID
5903
NCBI Gene
HGNC ID
HGNC:9848
HGNC
Ensembl
ENSG00000153201
NCBI Gene
Aliases
ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P49792E3 SUMO-protein ligase RanBP23,22433Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1460888P49792Espacenet
EP 4650780 A22025-11-193195P49792Espacenet
EP 4641201 A22025-10-292758P49792Espacenet
JP 2025517969 A2025-06-122758P49792Espacenet
JP 2025517970 A2025-06-123195P49792Espacenet
JP 2025032204 A2025-03-1134565P49792Espacenet
WO 2024240908 A12024-11-2839P49792Espacenet
EP 4461818 A22024-11-1334565P49792Espacenet
JP 2023058610 A2023-04-2534565P49792Espacenet
KR 1020230019756 A2023-02-097P49792Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,557

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRANBP2 papersNewest fiscal year
R01AI052014HIV-1 Preintegration Trafficking and Nuclear Localization202025
P30CA008748Cancer Center Support Grant172025
P30CA016672Cancer Center Support Grant132025
P30EY005722Center Core Grant for Vision Research132025
P30CA021765Cancer Center Support Grant (CCSG)102025
R01AI120860Development of HIV capsid-targeting antivirals that affect immune response by modulating capsid stability and have improved resistance profiles82025
R37AI039394Biochemical Mechanism of HIV DNA Integration82025
R01AI100720Evolutionary potential of HIV-1 capsid: mechanisms and consequences62025
R01GM117360Molecular Basis of mRNA Export62025
ZIAHD008954Mitotic roles of the Nuclear Transport Machinery62025

1 to 10 of 1,557Source NIH's project files

See all 1,557 nih grants

Papers2,505

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Rare-ID: Genomic Diagnosis in Symptomatic Neonates and Young Infants with Complex Clinical Phenotypes: A Descriptive Cohort Study.Genes (Basel)202642650144PubTator, text miningPubMed
Familial acute necrotizing encephalopathy temporally associated with SARS-CoV-2 infection: Two case reports and literature review.Medicine (Baltimore)202642629733PubTator, text miningPubMed
OGT-mediated O-GlcNAcylation of BICD2 drives gemcitabine resistance in pancreatic cancer via accelerating G2/M cell cycle progression.Drug Resist Updat202642600365PubTator, text miningPubMed
RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma.Cell Death Differ202642557375PubTator, text miningPubMed
Spatial control of mitochondrial retrograde signaling by nuclear pore-associated contact sites.bioRxiv202642539211PubTator, text miningPubMed
Variable Phenotype in Three Siblings With RAN Binding Protein 2 Variant With Potential Preventive Treatment for Recurrences.Pediatr Neurol202642407393PubTator, text miningPubMed
Familial, recurrent or genetic acute necrotizing encephalopathy of childhood: a systematic review and a case report. Focus on atypical events and on the role on immunizations.Eur J Paediatr Neurol202642385467PubTator, text miningPubMed
SUMOylation of HMGCS1 triggers its ubiquitin-dependent degradation to alleviate hepatic steatosis.Metabolism202642323980PubTator, text miningPubMed
Acute necrotizing encephalopathy associated with COVID-19 in a pediatric patient and a systematic review.J Hum Immun202642170325PubTator, text miningPubMed
RanBP2-dependent SUMOylation of G3BP2 inhibits formation, and promotes disassembly, of stress granules.Mol Biol Cell202642160509PubTator, text miningPubMed

1 to 10 of 2,505

See all 2,505 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5903

GET https://conductscience.org/api/genes/v1/5903/patents?page=2