Gene · 5903
RANBP2: RAN binding protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RANBP2: RAN binding protein 2. Genes, record 5903. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5903
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P49792 | E3 SUMO-protein ligase RanBP2 | 3,224 | 33 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 60888 | P49792 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3195 | P49792 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2758 | P49792 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2758 | P49792 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3195 | P49792 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 34565 | P49792 | Espacenet |
| WO 2024240908 A1 | 2024-11-28 | 39 | P49792 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 34565 | P49792 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 34565 | P49792 | Espacenet |
| KR 1020230019756 A | 2023-02-09 | 7 | P49792 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,557
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RANBP2 papers | Newest fiscal year |
|---|---|---|---|
| R01AI052014 | HIV-1 Preintegration Trafficking and Nuclear Localization | 20 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 17 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 13 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 13 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 10 | 2025 |
| R01AI120860 | Development of HIV capsid-targeting antivirals that affect immune response by modulating capsid stability and have improved resistance profiles | 8 | 2025 |
| R37AI039394 | Biochemical Mechanism of HIV DNA Integration | 8 | 2025 |
| R01AI100720 | Evolutionary potential of HIV-1 capsid: mechanisms and consequences | 6 | 2025 |
| R01GM117360 | Molecular Basis of mRNA Export | 6 | 2025 |
| ZIAHD008954 | Mitotic roles of the Nuclear Transport Machinery | 6 | 2025 |
1 to 10 of 1,557Source NIH's project files
See all 1,557 nih grantsPapers2,505
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Rare-ID: Genomic Diagnosis in Symptomatic Neonates and Young Infants with Complex Clinical Phenotypes: A Descriptive Cohort Study. | Genes (Basel) | 2026 | 42650144 | PubTator, text mining | PubMed |
| Familial acute necrotizing encephalopathy temporally associated with SARS-CoV-2 infection: Two case reports and literature review. | Medicine (Baltimore) | 2026 | 42629733 | PubTator, text mining | PubMed |
| OGT-mediated O-GlcNAcylation of BICD2 drives gemcitabine resistance in pancreatic cancer via accelerating G2/M cell cycle progression. | Drug Resist Updat | 2026 | 42600365 | PubTator, text mining | PubMed |
| RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma. | Cell Death Differ | 2026 | 42557375 | PubTator, text mining | PubMed |
| Spatial control of mitochondrial retrograde signaling by nuclear pore-associated contact sites. | bioRxiv | 2026 | 42539211 | PubTator, text mining | PubMed |
| Variable Phenotype in Three Siblings With RAN Binding Protein 2 Variant With Potential Preventive Treatment for Recurrences. | Pediatr Neurol | 2026 | 42407393 | PubTator, text mining | PubMed |
| Familial, recurrent or genetic acute necrotizing encephalopathy of childhood: a systematic review and a case report. Focus on atypical events and on the role on immunizations. | Eur J Paediatr Neurol | 2026 | 42385467 | PubTator, text mining | PubMed |
| SUMOylation of HMGCS1 triggers its ubiquitin-dependent degradation to alleviate hepatic steatosis. | Metabolism | 2026 | 42323980 | PubTator, text mining | PubMed |
| Acute necrotizing encephalopathy associated with COVID-19 in a pediatric patient and a systematic review. | J Hum Immun | 2026 | 42170325 | PubTator, text mining | PubMed |
| RanBP2-dependent SUMOylation of G3BP2 inhibits formation, and promotes disassembly, of stress granules. | Mol Biol Cell | 2026 | 42160509 | PubTator, text mining | PubMed |
1 to 10 of 2,505
See all 2,505 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5903
GET https://conductscience.org/api/genes/v1/5903/patents?page=2