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RAP1A: RAP1A, member of RAS oncogene family

1 protein, 87 patents, 0 drugs, 0 trials, 3,682 NIH grants and 6,973 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRAP1AHGNC
NameRAP1A, member of RAS oncogene familyHGNC
NCBI Gene ID5906NCBI Gene
HGNC IDHGNC:9855HGNC
EnsemblENSG00000116473NCBI Gene
AliasesC21KG, G-22K, KREV-1, KREV1, RAP1, SMGP21NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P62834Ras-related protein Rap-1A1844Ensembl, GeneID, HGNCUniProt

Patents 87

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-093P62834Espacenet
EP 4759327 A22026-06-1744P62834Espacenet
US 12648964 B22026-06-0920P62834Espacenet
EP 4650780 A22025-11-197291P62834Espacenet
JP 2025517970 A2025-06-127291P62834Espacenet
US 12291557 B22025-05-0656P62834Espacenet
JP 2025020284 A2025-02-12123P62834Espacenet
US 12181474 B22024-12-317P62834Espacenet
JP 2024123008 A2024-09-108082P62834Espacenet
JP 2024123008 A2024-09-108083P62834Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3682

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant162,025NIH's project files
P30CA016672Cancer Center Support Grant162,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase142,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant122,025NIH's project files
R01EY017011Endothelial Transmigration in Neovascular Age-related Macular Degeneration102,025NIH's project files
P30EY014800University of Utah Core Vision Research Grant92,025NIH's project files
R01AG016642Mechanism of the telomeric proliferation limit82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30CA016058Cancer Center Support Grant72,025NIH's project files
P30CA016086Cancer Center Support Grant72,025NIH's project files

Papers 6973

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825489PubTator, text miningPubMed
42794595PubTator, text miningPubMed
42793190PubTator, text miningPubMed
42792910PubTator, text miningPubMed
42765499PubTator, text miningPubMed
42736044PubTator, text miningPubMed
42716012PubTator, text miningPubMed
42707260PubTator, text miningPubMed
42706752PubTator, text miningPubMed
42634200PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license