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RARA: retinoic acid receptor alpha

1 protein, 96 patents, 11 drugs, 505 trials, 5,296 NIH grants and 11,393 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRARAHGNC
Nameretinoic acid receptor alphaHGNC
NCBI Gene ID5914NCBI Gene
HGNC IDHGNC:9864HGNC
EnsemblENSG00000131759NCBI Gene
AliasesNR1B1, RAR, RAR-alpha, RARalphaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10276Retinoic acid receptor alpha46214Ensembl, GeneID, HGNCUniProt

Patents 96

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461521P10276Espacenet
JP 2026004568 A2026-01-1461525P10276Espacenet
EP 4650780 A22025-11-191480P10276Espacenet
EP 4641201 A22025-10-291098P10276Espacenet
JP 2025147176 A2025-10-0615548P10276Espacenet
JP 2025532979 A2025-10-03152P10276Espacenet
EP 4593850 A22025-08-06152P10276Espacenet
JP 2025517969 A2025-06-121098P10276Espacenet
JP 2025517970 A2025-06-121480P10276Espacenet
US 12295971 B22025-05-13152P10276Espacenet

Drugs 11

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACITRETINCHEMBL1131Retinoid receptor agonistAGONISTChEMBL
ADAPALENECHEMBL1265Retinoic acid receptor agonistAGONISTChEMBL
ALITRETINOINCHEMBL705Retinoid receptor agonistAGONISTChEMBL
ETRETINATECHEMBL464Retinoid receptor agonistAGONISTChEMBL
IRX4310CHEMBL3545173Retinoic acid receptor antagonistANTAGONISTChEMBL
ISOTRETINOINCHEMBL547Retinoic acid receptor agonistAGONISTChEMBL
MOFAROTENECHEMBL146506Retinoid receptor modulatorMODULATORChEMBL
NRX195183CHEMBL107430Retinoic acid receptor alpha agonistAGONISTChEMBL
TAMIBAROTENECHEMBL25202Retinoic acid receptor alpha agonistAGONISTChEMBL
TAZAROTENECHEMBL1657Retinoic acid receptor agonistAGONISTChEMBL

Trials 505

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07597395TRETINOINPHASE3ClinicalTrials.gov
NCT07586826TRETINOINPHASE2ClinicalTrials.gov
NCT07586813TRETINOINPHASE2ClinicalTrials.gov
NCT07524946ADAPALENEPHASE4ClinicalTrials.gov
NCT07504458TRETINOINPHASE3ClinicalTrials.gov
NCT07503730TRETINOINPHASE3ClinicalTrials.gov
NCT07485777TRETINOINClinicalTrials.gov
NCT07481370ISOTRETINOINPHASE2ClinicalTrials.gov
NCT07473895ADAPALENEPHASE2ClinicalTrials.gov
NCT07469228TRETINOINPHASE1ClinicalTrials.gov

NIH grants 5296

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant582,025NIH's project files
P30CA008748Cancer Center Support Grant552,025NIH's project files
P30CA006973Regional Oncology Research Center212,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)202,025NIH's project files
P30CA016058Cancer Center Support Grant162,025NIH's project files
P30CA091842Cancer Center Support Grant162,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant132,025NIH's project files
P30CA023108Cancer Center Support Grant132,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant132,025NIH's project files
P30CA047904Cancer Center Support Grant112,025NIH's project files

Papers 11393

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823066PubTator, text miningPubMed
42818011PubTator, text miningPubMed
42774993PubTator, text miningPubMed
42761251PubTator, text miningPubMed
42705610PubTator, text miningPubMed
42686974PubTator, text miningPubMed
42663568PubTator, text miningPubMed
42660821PubTator, text miningPubMed
42610425PubTator, text miningPubMed
42530534PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license