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RARB: retinoic acid receptor beta

1 protein, 40 patents, 10 drugs, 501 trials, 2,958 NIH grants and 5,323 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRARBHGNC
Nameretinoic acid receptor betaHGNC
NCBI Gene ID5915NCBI Gene
HGNC IDHGNC:9865HGNC
EnsemblENSG00000077092NCBI Gene
AliasesHAP, MCOPS12, NR1B2, RAR-beta, RARbeta, RARbeta1, RRB2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10826Retinoic acid receptor beta4559Ensembl, GeneID, HGNCUniProt

Patents 40

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-0615549P10826Espacenet
US 12280021 B22025-04-2262P10826Espacenet
US 12280021 B22025-04-2263P10826Espacenet
US 12269793 B22025-04-0862P10826Espacenet
US 12269793 B22025-04-0863P10826Espacenet
JP 2025028160 A2025-02-2815549P10826Espacenet
KR 1020250010750 A2025-01-2115549P10826Espacenet
JP 2024123008 A2024-09-108184P10826Espacenet
JP 2024109657 A2024-08-1415388P10826Espacenet
EP 4257186 A22023-10-1162P10826Espacenet

Drugs 10

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACITRETINCHEMBL1131Retinoid receptor agonistAGONISTChEMBL
ADAPALENECHEMBL1265Retinoic acid receptor agonistAGONISTChEMBL
ALITRETINOINCHEMBL705Retinoid receptor agonistAGONISTChEMBL
ETRETINATECHEMBL464Retinoid receptor agonistAGONISTChEMBL
IRX4310CHEMBL3545173Retinoic acid receptor antagonistANTAGONISTChEMBL
ISOTRETINOINCHEMBL547Retinoic acid receptor agonistAGONISTChEMBL
MOFAROTENECHEMBL146506Retinoid receptor modulatorMODULATORChEMBL
TAMIBAROTENECHEMBL25202Retinoic acid receptor beta agonistAGONISTChEMBL
TAZAROTENECHEMBL1657Retinoic acid receptor agonistAGONISTChEMBL
TRETINOINCHEMBL38Retinoic acid receptor agonistAGONISTChEMBL

Trials 501

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07597395TRETINOINPHASE3ClinicalTrials.gov
NCT07586826TRETINOINPHASE2ClinicalTrials.gov
NCT07586813TRETINOINPHASE2ClinicalTrials.gov
NCT07524946ADAPALENEPHASE4ClinicalTrials.gov
NCT07504458TRETINOINPHASE3ClinicalTrials.gov
NCT07503730TRETINOINPHASE3ClinicalTrials.gov
NCT07485777TRETINOINClinicalTrials.gov
NCT07481370ISOTRETINOINPHASE2ClinicalTrials.gov
NCT07473895ADAPALENEPHASE2ClinicalTrials.gov
NCT07469228TRETINOINPHASE1ClinicalTrials.gov

NIH grants 2958

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant352,025NIH's project files
P30CA006973Regional Oncology Research Center192,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan132,025NIH's project files
P30CA016058Cancer Center Support Grant112,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility102,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant72,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center72,025NIH's project files
P30DK035816Nutrition Obesity Research Center72,025NIH's project files
P30DK063491Diabetes Research Center (DRC)72,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)72,025NIH's project files

Papers 5323

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821807PubTator, text miningPubMed
42667103PubTator, text miningPubMed
42650885PubTator, text miningPubMed
42601645PubTator, text miningPubMed
42533031PubTator, text miningPubMed
42492627PubTator, text miningPubMed
42469952PubTator, text miningPubMed
42444941PubTator, text miningPubMed
42230504PubTator, text miningPubMed
42101681PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license