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Gene · 5916

RARG: retinoic acid receptor gamma

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RARG: retinoic acid receptor gamma. Genes, record 5916. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5916

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Gene

Symbol
RARG
HGNC
Name
retinoic acid receptor gamma
HGNC
NCBI Gene ID
5916
NCBI Gene
HGNC ID
HGNC:9866
HGNC
Ensembl
ENSG00000172819
NCBI Gene
Aliases
NR1B3, RAR-gamma, RARC, RARgamma
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13631Retinoic acid receptor gamma45411Ensembl, GeneID, HGNC

Source UniProt

Patents46

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461530P13631Espacenet
JP 2026004568 A2026-01-1461531P13631Espacenet
EP 4650780 A22025-11-1912246P13631Espacenet
EP 4640849 A22025-10-291980P13631Espacenet
EP 4641201 A22025-10-2913305P13631Espacenet
EP 4641202 A22025-10-296150P13631Espacenet
JP 2025147176 A2025-10-0615550P13631Espacenet
JP 2025519096 A2025-06-241980P13631Espacenet
JP 2025517969 A2025-06-1213305P13631Espacenet
JP 2025517970 A2025-06-1212246P13631Espacenet

1 to 10 of 46

See all 46 patents

Drugs11

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ACITRETINCHEMBL1131Retinoid receptor agonistAGONISTChEMBL
ADAPALENECHEMBL1265Retinoic acid receptor agonistAGONISTChEMBL
ALITRETINOINCHEMBL705Retinoid receptor agonistAGONISTChEMBL
ETRETINATECHEMBL464Retinoid receptor agonistAGONISTChEMBL
IRX4310CHEMBL3545173Retinoic acid receptor antagonistANTAGONISTChEMBL
ISOTRETINOINCHEMBL547Retinoic acid receptor agonistAGONISTChEMBL
MOFAROTENECHEMBL146506Retinoid receptor modulatorMODULATORChEMBL
PALOVAROTENECHEMBL2105648Retinoic acid receptor gamma agonistAGONISTChEMBL
TAZAROTENECHEMBL1657Retinoic acid receptor agonistAGONISTChEMBL
TRETINOINCHEMBL38Retinoic acid receptor agonistAGONISTChEMBL

1 to 10 of 11

See all 11 drugs

Trials502

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,608

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRARG papersNewest fiscal year
P30CA016672Cancer Center Support Grant112025
P30CA016058Cancer Center Support Grant82025
P30CA006973Regional Oncology Research Center52025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025
P30CA008748Cancer Center Support Grant42025
P30CA023108Cancer Center Support Grant42025
T32CA009512Clinical Scholars Biomedical Research Training Program42025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer32025
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)32025

1 to 10 of 1,608Source NIH's project files

See all 1,608 nih grants

Papers2,651

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Rare Cancer-Associated Mutations May Affect the AF1 Phosphoregulatory Domain of RARγ.Genes (Basel)202642793013PubTator, text miningPubMed
Dual HBV cccDNA-linked HiBiT reporter hepatocyte models for screening of candidate cccDNA modulators.Virulence202642697841PubTator, text miningPubMed
Stable simulations do not guarantee functional engagement: a case study of off-target prediction for Seladelpar and Zanamivir.J Comput Aided Mol Des202642690469PubTator, text miningPubMed
Genomic diversification between aposematic and cryptic phenotypes of Oophaga granulifera (Anura: Dendrobatidae).Sci Rep202642661044PubTator, text miningPubMed
Barrier Function and Biophysical Effects of 0.104% and 0.247% Retinol Creams in Mature Facial Skin: A Prospective Study.Int J Mol Sci202642653210PubTator, text miningPubMed
Trifarotene for Facial and Truncal Acne Vulgaris: A Narrative Review of Clinical Trial Evidence.Cureus202642615018PubTator, text miningPubMed
Successful Trifarotene Treatment of a Typical Kyrle's Disease With Overview of Topical Therapies.Skin Res Technol202642480558PubTator, text miningPubMed
Structural and Thermodynamic Discrimination between Agonists and Antagonists of Retinoic Acid Receptor γ and the Vitamin D Receptor.J Chem Inf Model202642378554PubTator, text miningPubMed
Am80 (tamibarotene) and ATRA induce highly similar molecular responses and myeloid differentiation in non-APL AML, enhanced by LSD1/GCN5 inhibition and increased RARA expression.BMC Cancer202642365243PubTator, text miningPubMed
Sex Differences in Cancer and Cardiotoxicity: Mechanisms, Outcomes, and Clinical Implications Across Solid and Hematological Malignancies.Cancers (Basel)202642279262PubTator, text miningPubMed

1 to 10 of 2,651

See all 2,651 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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