Gene · 5921
RASA1: RAS p21 protein activator 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RASA1: RAS p21 protein activator 1. Genes, record 5921. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5921
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P20936 | Ras GTPase-activating protein 1 | 1,047 | 15 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2903 | P20936 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2468 | P20936 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2468 | P20936 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2903 | P20936 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8123 | P20936 | Espacenet |
| JP 2023123507 A | 2023-09-05 | 289 | P20936 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 71877 | P20936 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 174848 | P20936 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 9375 | P20936 | Espacenet |
| JP 2020524809 A | 2020-08-20 | 289 | P20936 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,330
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RASA1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 41 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| P01AI091580 | Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR | 9 | 2025 |
| ZIACL080017 | IQGAP1 in tumorigenesis | 9 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
| R35GM118177 | Excitable Networks in Directed Cell Migration | 6 | 2025 |
| ZIABC010440 | Protein Structure, Stability, and Amyloid Formation | 6 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 5 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
1 to 10 of 2,330Source NIH's project files
See all 2,330 nih grantsPapers3,549
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Ras protein activator-like 3 is a key Ras GTPase-activating protein that protects the survival and anti-tumor activity of CD8+ T cells. | Front Immunol | 2026 | 42819241 | PubTator, text mining | PubMed |
| Clinical and molecular characterization of non-PIK3CA-related vascular malformations with overgrowth in a pediatric cohort. | World J Pediatr | 2026 | 42814223 | PubTator, text mining | PubMed |
| Macrophage phagocytosis checkpoints in DLBCL immunotherapy: an evidence-maturity framework from CD47 to CD200. | Front Oncol | 2026 | 42798844 | PubTator, text mining | PubMed |
| New Biochemical Insights into RIT GTPases Regulation and Membrane Interactions. | Cells | 2026 | 42738861 | PubTator, text mining | PubMed |
| Management of Combined Vascular Malformations. | Clin Plast Surg | 2026 | 42680450 | PubTator, text mining | PubMed |
| Changes in Ras and Ras-Associated GTPases During Maturation of Porcine Cumulus Cells and Oocytes. | Animals (Basel) | 2026 | 42511004 | PubTator, text mining | PubMed |
| Cardiac remodelling and dysfunction in cancer patients receiving cardiotoxic therapies: proteomic and metabolomic profiling. | Eur Heart J | 2026 | 42366805 | PubTator, text mining | PubMed |
| Capillary Malformation-Arteriovenous Malformation Syndrome Associated with RASA1 and EPHB4 Mutations: Comparative Case Series and Narrative Review. | Life (Basel) | 2026 | 42355527 | PubTator, text mining | PubMed |
| MiR-31 as a predictive biomarker of cetuximab efficacy in metastatic colorectal cancer patients: systematic review. | Clin Transl Oncol | 2026 | 42315817 | PubTator, text mining | PubMed |
| The RASA2/RASA3 ortholog RasGAP1 modulates obesity-linked phenotypes and is associated with leptin-analog signaling in Drosophila. | Front Endocrinol (Lausanne) | 2026 | 42244947 | PubTator, text mining | PubMed |
1 to 10 of 3,549
See all 3,549 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5921
GET https://conductscience.org/api/genes/v1/5921/patents?page=2