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RB1: RB transcriptional corepressor 1

1 protein, 115 patents, 0 drugs, 0 trials, 12,815 NIH grants and 38,467 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRB1HGNC
NameRB transcriptional corepressor 1HGNC
NCBI Gene ID5925NCBI Gene
HGNC IDHGNC:9884HGNC
EnsemblENSG00000139687NCBI Gene
AliasesOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P06400Retinoblastoma-associated protein92819Ensembl, GeneID, HGNCUniProt

Patents 115

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026102714 A2026-06-233P06400Espacenet
JP 2026515744 A2026-05-19223P06400Espacenet
WO 2026054021 A2026-03-122P06400Espacenet
WO 2026054022 A2026-03-122P06400Espacenet
JP 2026000973 A2026-01-062P06400Espacenet
EP 4650780 A22025-11-192604P06400Espacenet
EP 4647424 A12025-11-122P06400Espacenet
US 12466828 B22025-11-113P06400Espacenet
EP 4641201 A22025-10-292187P06400Espacenet
KR 1020250153810 A2025-10-272P06400Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 12815

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant5172,025NIH's project files
P30CA016672Cancer Center Support Grant4112,025NIH's project files
P30CA006973Regional Oncology Research Center942,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)912,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE882,025NIH's project files
P30CA016058Cancer Center Support Grant632,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant572,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant572,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028562,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase532,025NIH's project files

Papers 38467

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824253PubTator, text miningPubMed
42823093PubTator, text miningPubMed
42814286PubTator, text miningPubMed
42811745PubTator, text miningPubMed
42809709PubTator, text miningPubMed
42801735PubTator, text miningPubMed
42794933PubTator, text miningPubMed
42790640PubTator, text miningPubMed
42783444PubTator, text miningPubMed
42779706PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license