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KDM5A: lysine demethylase 5A
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Gene · 5927

Papers1,684

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 1,684

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TitleJournalYearPMIDFound bySource
m5C RNA methylation is dysregulated by oncogenic herpesviruses via c-Myc signaling to counteract host antiviral factors.Nucleic Acids Res202641873763PubTator, text miningPubMed
Noncanonical role of KDM5C in conferring bortezomib resistance via the PERK‒Nrf2 axis in multiple myeloma.Cell Death Dis202641872155PubTator, text miningPubMed
Decoding Adipose Tissue Phenotypic Switching: From Mechanisms to Computational Drug Discovery.Curr Obes Rep202641866446PubTator, text miningPubMed
Protein Phosphatase 2 Is Required for Metastatic Dormancy and Is Regulated by Histone Demethylase KDM5A.Mol Carcinog202641849698PubTator, text miningPubMed
Beyond blacklists: a critical assessment of exclusion set generation strategies and alternative approaches.Bioinformatics202641826793PubTator, text miningPubMed
Ubiquitin-mediated stabilization of KDM5B drives chemoresistance via repression of dual-specificity phosphatase 4 in ovarian cancer.Signal Transduct Target Ther202641813651PubTator, text miningPubMed
KDM5D expression is lost in cisplatin‑resistant neuroblastoma cells.Oncol Rep202641789643PubTator, text miningPubMed
miR-1290 serves as a potential biomarker for osteoporotic fracture and regulates osteoblast function by targeting KDM5A.J Orthop Surg Res202641782000PubTator, text miningPubMed
FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation.Cell Biol Toxicol202641781602PubTator, text miningPubMed
Emerging roles of RNA N5-methylcytosine modification in reproductive physiology and gynecological diseases.Epigenetics202641778387PubTator, text miningPubMed
Genomic landscape of pediatric germ cell tumors reveals oncogenic mutations and copy number alterations.Front Oncol202641777659PubTator, text miningPubMed
Uncovering mitochondrial dynamics-related genes as potential diagnostic biomarkers for acute myocardial infarction.Front Cardiovasc Med202641768570PubTator, text miningPubMed
Integrative metabolomics and machine learning reveal the toxic mechanisms of elaidic acid in polycystic ovary syndrome.Reprod Toxicol202641747841PubTator, text miningPubMed
Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis.Nat Commun202641735293PubTator, text miningPubMed
A multi-omics approach elucidates the link between artificial food colorings and common cancers.Front Nutr202641727196PubTator, text miningPubMed
ERRα-KDM5C restrains STING enhancer activity to modulate type I interferon signaling in breast cancer progression.Cell Death Dis202641708589PubTator, text miningPubMed
Bioinformatics identification and experimental validation of hub genes associated with narcolepsy type 1.J Clin Transl Sci202641694065PubTator, text miningPubMed
A system-level metastable model of cancer evolution: integrating replication stress, cell cycle deregulation and chromosomal instability.Ann Med202641606986PubTator, text miningPubMed
Cholesterol in glioblastoma: Impaired Hh signaling enhances epigenetic modifiers and decreases CAV1.Cell Struct Funct202641605664PubTator, text miningPubMed
Genomic divergence between matched primary and metastatic tumors across cancer types: a pan-cancer analysis of 5,692 samples.Expert Rev Anticancer Ther202641354463PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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