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ACE2: angiotensin converting enzyme 2

1 protein, 246 patents, 0 drugs, 0 trials, 8,956 NIH grants and 53,694 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolACE2HGNC
Nameangiotensin converting enzyme 2HGNC
NCBI Gene ID59272NCBI Gene
HGNC IDHGNC:13557HGNC
EnsemblENSG00000130234NCBI Gene
AliasesACEHNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9BYF1Angiotensin-converting enzyme 2805348Ensembl, GeneID, HGNCUniProt

Patents 246

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026123111 A2026-07-295Q9BYF1Espacenet
US 12649770 B22026-06-0913Q9BYF1Espacenet
JP 2026074030 A2026-05-0112Q9BYF1Espacenet
US 12605438 B22026-04-214Q9BYF1Espacenet
JP 2026503220 A2026-01-2828Q9BYF1Espacenet
JP 2026006543 A2026-01-161Q9BYF1Espacenet
WO 2025262023 A12025-12-2615Q9BYF1Espacenet
WO 2025262025 A12025-12-2615Q9BYF1Espacenet
WO 2025262082 A12025-12-2615Q9BYF1Espacenet
EP 4667578 A22025-12-24260Q9BYF1Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8956

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001863Yale Clinical and Translational Science Award742,025NIH's project files
P30CA008748Cancer Center Support Grant512,025NIH's project files
U19AI135972SARS-CoV adaptations through a Systems Biology Lens (SYBIL)472,025NIH's project files
P51OD011132Emory National Primate Research Center462,025NIH's project files
P51OD011104Tulane National Primate Research Center452,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success392,025NIH's project files
UM1AI144462Consortium for HIV/AIDS Vaccine Development382,025NIH's project files
U19AI135995Center for Viral Systems Biology (CViSB)342,025NIH's project files
T32AI007245Molecular Basis of Viral Infectivity322,025NIH's project files
R01AI129269Olfactory and neurological manifestations of acute and post-acute murine COVID-19272,025NIH's project files

Papers 53694

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826581PubTator, text miningPubMed
42825912PubTator, text miningPubMed
42824800PubTator, text miningPubMed
42821519PubTator, text miningPubMed
42821509PubTator, text miningPubMed
42821038PubTator, text miningPubMed
42818453PubTator, text miningPubMed
42807861PubTator, text miningPubMed
42798753PubTator, text miningPubMed
42796707PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license