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CCND1: cyclin D1

1 protein, 160 patents, 3 drugs, 313 trials, 16,784 NIH grants and 71,721 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCCND1HGNC
Namecyclin D1HGNC
NCBI Gene ID595NCBI Gene
HGNC IDHGNC:1582HGNC
EnsemblENSG00000110092NCBI Gene
AliasesBCL1, D11S287E, PRAD1, U21B31NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P24385G1/S-specific cyclin-D129511Ensembl, GeneID, HGNCUniProt

Patents 160

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12661384 B22026-06-2316P24385Espacenet
WO 2026017877 A12026-01-2218P24385Espacenet
EP 4650780 A22025-11-19683P24385Espacenet
JP 2025166836 A2025-11-0627P24385Espacenet
EP 4641201 A22025-10-29480P24385Espacenet
EP 4641202 A22025-10-294361P24385Espacenet
JP 2025517969 A2025-06-12480P24385Espacenet
JP 2025517970 A2025-06-12683P24385Espacenet
US 12264339 B22025-04-0155P24385Espacenet
JP 2025032204 A2025-03-1125963P24385Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BRICICLIBCHEMBL1206245G1/S-specific cyclin D1 inhibitorINHIBITORChEMBL
PALBOCICLIBCHEMBL189963CDK6/cyclin D1 inhibitorINHIBITORChEMBL
PALBOCICLIBCHEMBL189963Cyclin-dependent kinase 4/cyclin D1 inhibitorINHIBITORChEMBL

Trials 313

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07543250PALBOCICLIBClinicalTrials.gov
NCT07493291PALBOCICLIBClinicalTrials.gov
NCT07299890PALBOCICLIBPHASE2ClinicalTrials.gov
NCT07191977PALBOCICLIBPHASE2ClinicalTrials.gov
NCT07178743PALBOCICLIBClinicalTrials.gov
NCT07174336PALBOCICLIBPHASE3ClinicalTrials.gov
NCT07123090PALBOCICLIBPHASE2ClinicalTrials.gov
NCT07096024PALBOCICLIBClinicalTrials.gov
NCT07061717PALBOCICLIBPHASE3ClinicalTrials.gov
NCT07002177PALBOCICLIBPHASE1/PHASE2ClinicalTrials.gov

NIH grants 16784

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant6602,025NIH's project files
P30CA008748Cancer Center Support Grant3682,025NIH's project files
P30CA016058Cancer Center Support Grant1132,025NIH's project files
P30CA006973Regional Oncology Research Center852,025NIH's project files
P30CA056036Translational Research in Cancer802,025NIH's project files
P30CA068485Cancer Center Support Grant782,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant732,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase702,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant702,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant632,025NIH's project files

Papers 71721

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827110PubTator, text miningPubMed
42826002PubTator, text miningPubMed
42824422PubTator, text miningPubMed
42823177PubTator, text miningPubMed
42822006PubTator, text miningPubMed
42816986PubTator, text miningPubMed
42815556PubTator, text miningPubMed
42815008PubTator, text miningPubMed
42814286PubTator, text miningPubMed
42812221PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license