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Gene · 5961

PRPH2: peripherin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PRPH2: peripherin 2. Genes, record 5961. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5961

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Gene

Symbol
PRPH2
HGNC
Name
peripherin 2
HGNC
NCBI Gene ID
5961
NCBI Gene
HGNC ID
HGNC:9942
HGNC
Ensembl
ENSG00000112619
NCBI Gene
Aliases
AOFMD, AVMD, CACD2, DS, MDBS1, RDS, RP7, TSPAN22, rd2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23942Peripherin-23461Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4821560 A22026-10-1419P23942Espacenet
JP 2026515744 A2026-05-19126P23942Espacenet
JP 2026004568 A2026-01-1457375P23942Espacenet
EP 4667578 A22025-12-24147P23942Espacenet
EP 4641201 A22025-10-29541P23942Espacenet
JP 2025131621 A2025-09-09147P23942Espacenet
JP 2025517969 A2025-06-12541P23942Espacenet
US 12310997 B22025-05-2713P23942Espacenet
US 12275959 B22025-04-1519P23942Espacenet
JP 2025039615 A2025-03-2119P23942Espacenet

1 to 10 of 66

See all 66 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants863

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRPH2 papersNewest fiscal year
R01EY010609Mechanism of photoreceptor cell degeneration in animal models of retinal diseases502025
R01EY018213Defining Barriers to Gene Therapy192025
R01EY018571Genetics of early onset retinal diseases122025
R01EY022356Molecular Basis of Human Visual System Disorders122025
P30EY000331Vision Research Core at UCLA112025
P30CA013696Cancer Center Support Grant102025
P30EY001792P30 Core Grant for Vision Research92025
P30EY005722Center Core Grant for Vision Research92025
R01EY012910Precision Medicine for Inherited Retinal Degenerations92025
R01EY024698Gene Editing and Silencing in Phototransduction92025

1 to 10 of 863Source NIH's project files

See all 863 nih grants

Papers1,698

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dissecting Missing Heritability in Rare Inherited Macular Dystrophies.Genes (Basel)202642650171PubTator, text miningPubMed
Homozygous ROM1 frameshift variant associated with late-onset retinal dystrophy.Ophthalmic Genet202642635054PubTator, text miningPubMed
CDHR1-associated retinal degeneration: Clinical phenotypes and therapeutic approaches.Prog Retin Eye Res202642562233PubTator, text miningPubMed
Strategies for Mitigation of Intermediate CO2 Poisoning to Promote Electrocatalytic Efficiency during Urea Oxidation Reaction.Chem Bio Eng202642376260PubTator, text miningPubMed
Clinical manifestations of dual-gene variants in retinitis pigmentosa.Acta Ophthalmol202642360046PubTator, text miningPubMed
Disease and Participant-Related Correlates of Genetic Testing Completion for Hereditary Eye Disorders in a Cohort of over 1400 Patients.Ophthalmol Sci202642358619PubTator, text miningPubMed
Insights into ANKRD11-related epilepsy from 163 people.Epilepsia202642322264PubTator, text miningPubMed
Inherited retinal disease genes with dual inheritance patterns: insights from the IRD-PT registry.J Med Genet202642321002PubTator, text miningPubMed
Investigating PRPH2-associated retinal degeneration patient-reported outcomes in vision-related quality of life.BMC Ophthalmol202642316356PubTator, text miningPubMed
PRPH2-associated retinal disease: dual inheritance and broad phenotypic spectrum in a Portuguese cohort.Eye (Lond)202642151405PubTator, text miningPubMed

1 to 10 of 1,698

See all 1,698 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5961

GET https://conductscience.org/api/genes/v1/5961/patents?page=2