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Gene · 5965

RECQL: RecQ like helicase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RECQL: RecQ like helicase. Genes, record 5965. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5965

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Gene

Symbol
RECQL
HGNC
Name
RecQ like helicase
HGNC
NCBI Gene ID
5965
NCBI Gene
HGNC ID
HGNC:9948
HGNC
Ensembl
ENSG00000004700
NCBI Gene
Aliases
RECON, RECQL1, RecQ1, RecQL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P46063ATP-dependent DNA helicase Q16497Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461191P46063Espacenet
JP 2026004568 A2026-01-1461192P46063Espacenet
EP 4650780 A22025-11-1912726P46063Espacenet
JP 2025517970 A2025-06-1212726P46063Espacenet
EP 4464338 A22024-11-20176P46063Espacenet
US 11834686 B22023-12-0557P46063Espacenet
US 11680268 B22023-06-20176P46063Espacenet
US 11597924 B22023-03-0749P46063Espacenet
US 11446398 B22022-09-2072165P46063Espacenet
US 11446398 B22022-09-2072166P46063Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants856

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRECQL papersNewest fiscal year
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability542025
ZIAAG000726Function of RecQ helicases in genome stability352025
ZIAAG000752Model Genetic Systems to Study DNA Repair262025
ZIAAG000753Fanconi Anemia Pathway262025
P01CA092584Structural Cell Biology of DNA Repair Machines142025
P30CA016672Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant82025
R01ES007061Mechanisms of DNA Double-strand Break End Resection and Repair Pathway Choice62025
R01GM058015Recombinational Mechanisms of DNA Repair62025
R01CA248526Mechanisms of replication fork protection and recovery52025

1 to 10 of 856Source NIH's project files

See all 856 nih grants

Papers1,260

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A transcription factor regulates development of a bacteria-housing eukaryotic cell through DNA damage mitigation.Proc Natl Acad Sci U S A202642784505PubTator, text miningPubMed
RECQL correlates with immune infiltration and serves as a prognostic biomarker and therapeutic predictor in gastric cancer.Transl Cancer Res202642724473PubTator, text miningPubMed
[WRN and Other RecQ Helicases in Life Cycles of Viruses].Mol Biol (Mosk)202642599232PubTator, text miningPubMed
FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability.Nat Commun202642380136PubTator, text miningPubMed
A multigene model for response stratification to neoadjuvant chemotherapy in triple negative breast cancer.Breast202641863200PubTator, text miningPubMed
Shuttling of RecQ helicase HIM-6 coordinates iterative cycle of unwinding, pulling, and backsliding.Nucleic Acids Res202641805131PubTator, text miningPubMed
Prognostic Significance of DNA Repair Gene mRNA Expression in Early-Stage Breast Cancer: Insights into Clinical Relevance.Oncol Res202641799499PubTator, text miningPubMed
DNA binding converts an inactive RecQ4-family helicase into a dominant-negative DNA repair factor.bioRxiv202641726939PubTator, text miningPubMed
Design and evaluation of semantically-valid negative samples integration techniques for scalable semi-automated drug repurposing prediction pipelines in rare disease research.BMC Bioinformatics202641639620PubTator, text miningPubMed
Precision Medicine Program in Chinese Pediatric Patients With Sarcoma.JCO Precis Oncol202641533994PubTator, text miningPubMed

1 to 10 of 1,260

See all 1,260 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5965

GET https://conductscience.org/api/genes/v1/5965/patents?page=2