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Gene · 5967

REG1A: regenerating family member 1 alpha

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. REG1A: regenerating family member 1 alpha. Genes, record 5967. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5967

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Gene

Symbol
REG1A
HGNC
Name
regenerating family member 1 alpha
HGNC
NCBI Gene ID
5967
NCBI Gene
HGNC ID
HGNC:9951
HGNC
Ensembl
ENSG00000115386
NCBI Gene
Aliases
ICRF, P19, PSP, PSPS, PSPS1, PTP, REG
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P05451Lithostathine-1-alpha1662Ensembl, GeneID, HGNC

Source UniProt

Patents66

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12656346 B22026-06-162P05451Espacenet
JP 2026004568 A2026-01-1461202P05451Espacenet
EP 4650780 A22025-11-19863P05451Espacenet
EP 4641201 A22025-10-29608P05451Espacenet
JP 2025147176 A2025-10-0611299P05451Espacenet
JP 2025529142 A2025-09-047542P05451Espacenet
US 12371689 B22025-07-297542P05451Espacenet
JP 2025517969 A2025-06-12608P05451Espacenet
JP 2025517970 A2025-06-12863P05451Espacenet
JP 2025028160 A2025-02-2811299P05451Espacenet

1 to 10 of 66

See all 66 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,122

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleREG1A papersNewest fiscal year
P30DK052574Host-environment interactions in the pathophysiology of digestive disease82025
P30CA015704Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA036727Buffett Cancer Center Support Grant32025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital32025
U01DK062422Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations32025
P01CA117969Genetics and Biology of Pancreatic Ductal Adenocarcinoma22025
P30AI094189The Johns Hopkins Center for AIDS Research (JHU CFAR)22025
P30CA016086Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025

1 to 10 of 1,122Source NIH's project files

See all 1,122 nih grants

Papers1,737

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Comparison of standard care versus a biomarker algorithm to guide antibiotic stewardship in pediatric intensive care unit: a prospective observational cohort study with historical control (the BASIP study).
Eur J Pediatr202642560479PubTator, text miningPubMed
Serum Pancreatic Stone Protein Across the Spectrum of Hypertensive Disorders of Pregnancy: Discrimination of Preeclampsia Compared with Conventional Inflammatory Indices.Medicina (Kaunas)202642512903PubTator, text miningPubMed
Plasma Proteomic Profiling Identifies Candidate Biomarkers for Pancreatic Ductal Adenocarcinoma.J Clin Lab Anal202642482375PubTator, text miningPubMed
Pancreatic Stone Protein in Burns: Clinical Value of Bedside Testing-A Prospective Pilot Study.Diagnostics (Basel)202642449910PubTator, text miningPubMed
Pancreatic Stone Protein as an Early Predictor of Adverse Events in Patients with Infection Presenting to the Emergency Department: A Pilot Study.J Pers Med202642346623PubTator, text miningPubMed
REG3A: A Potential Fecal Biomarker for Ulcerative Colitis.Mediators Inflamm202642345560PubTator, text miningPubMed
Pancreatic Stone Protein as an Emerging Biomarker in Paediatric Nosocomial and Postoperative Sepsis: An Integrative Review of Diagnostic and Prognostic Performance.Int J Mol Sci202642278356PubTator, text miningPubMed
NFYA Activates REG1A Expression to Promote Malignant Progression and Chemosensitivity in Rectal Cancer.Ann Clin Lab Sci202642259544PubTator, text miningPubMed
Human Metapneumovirus G Protein Immunogenicity and Safety Explored via Carrier Protein Fusion.Trop Med Infect Dis202642188864PubTator, text miningPubMed
Single-nucleus RNA sequencing reveals the effects of key regulators on human pancreatic adenocarcinoma and its tumor microenvironment.J Gastrointest Oncol202642169874PubTator, text miningPubMed

1 to 10 of 1,737

See all 1,737 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5967

GET https://conductscience.org/api/genes/v1/5967/patents?page=2