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BCL2A1: BCL2 related protein A1

1 protein, 109 patents, 2 drugs, 19 trials, 8,852 NIH grants and 16,155 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBCL2A1HGNC
NameBCL2 related protein A1HGNC
NCBI Gene ID597NCBI Gene
HGNC IDHGNC:991HGNC
EnsemblENSG00000140379NCBI Gene
AliasesACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q16548Bcl-2-related protein A117526Ensembl, GeneID, HGNCUniProt

Patents 109

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026086637 A2026-05-2681Q16548Espacenet
US 12466853 B22025-11-1181Q16548Espacenet
EP 4641202 A22025-10-294617Q16548Espacenet
JP 2025147176 A2025-10-0614722Q16548Espacenet
JP 2025062604 A2025-04-148861Q16548Espacenet
JP 2025028160 A2025-02-2814722Q16548Espacenet
KR 1020250017231 A2025-02-044617Q16548Espacenet
KR 1020250010750 A2025-01-2114722Q16548Espacenet
JP 2024123008 A2024-09-105067Q16548Espacenet
JP 2024109657 A2024-08-1414561Q16548Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
OBATOCLAXCHEMBL408194Bcl-2-related protein A1 inhibitorINHIBITORChEMBL
OBATOCLAX MESYLATECHEMBL2107358Bcl-2-related protein A1 inhibitorINHIBITORChEMBL

Trials 19

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01563601OBATOCLAX MESYLATEPHASE3ClinicalTrials.gov
NCT01238146OBATOCLAX MESYLATEPHASE1/PHASE2ClinicalTrials.gov
NCT00933985OBATOCLAX MESYLATEPHASE1ClinicalTrials.gov
NCT00918931OBATOCLAX MESYLATEPHASE22011-04-25ClinicalTrials.gov
NCT00724841OBATOCLAX MESYLATEPHASE1/PHASE2ClinicalTrials.gov
NCT00719901OBATOCLAX MESYLATEPHASE1/PHASE22013-12-09ClinicalTrials.gov
NCT00684918OBATOCLAXPHASE2ClinicalTrials.gov
NCT00682981OBATOCLAXPHASE1/PHASE2ClinicalTrials.gov
NCT00612612OBATOCLAX MESYLATEPHASE1ClinicalTrials.gov
NCT00600964OBATOCLAX MESYLATEPHASE1ClinicalTrials.gov

NIH grants 8852

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant682,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)242,025NIH's project files
R01DK018381Studies on the structure of basement membranes232,025NIH's project files
P30CA068485Cancer Center Support Grant132,025NIH's project files
P01CA163222Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment122,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase112,025NIH's project files
P30CA013330Cancer Center Support Grant112,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)102,025NIH's project files

Papers 16155

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42802645PubTator, text miningPubMed
42794618PubTator, text miningPubMed
42771701PubTator, text miningPubMed
42764777PubTator, text miningPubMed
42753930PubTator, text miningPubMed
42753887PubTator, text miningPubMed
42743047PubTator, text miningPubMed
42733572PubTator, text miningPubMed
42706449PubTator, text miningPubMed
42696602PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license