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RELA: RELA proto-oncogene, NF-kB subunit

1 protein, 75 patents, 1 drug, 4 trials, 16,891 NIH grants and 50,147 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRELAHGNC
NameRELA proto-oncogene, NF-kB subunitHGNC
NCBI Gene ID5970NCBI Gene
HGNC IDHGNC:9955HGNC
EnsemblENSG00000173039NCBI Gene
AliasesAIF3BL3, CMCU, NFKB3, p65NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q04206Transcription factor p6555188Ensembl, GeneID, HGNCUniProt

Patents 75

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026035773 A2026-03-0412Q04206Espacenet
US 12559530 B22026-02-24117Q04206Espacenet
JP 2026004568 A2026-01-1469760Q04206Espacenet
JP 2025540186 A2025-12-11403Q04206Espacenet
EP 4650780 A22025-11-1911794Q04206Espacenet
EP 4641201 A22025-10-2912545Q04206Espacenet
EP 4630045 A22025-10-15403Q04206Espacenet
JP 2025147176 A2025-10-0615564Q04206Espacenet
KR 1020250129816 A2025-08-29403Q04206Espacenet
JP 2025524002 A2025-07-2532Q04206Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
EDASALONEXENTCHEMBL3786673Nuclear factor NF-kappa-B complex inhibitorINHIBITORChEMBL

Trials 4

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03917719EDASALONEXENTPHASE3ClinicalTrials.gov
NCT03703882EDASALONEXENTPHASE32022-06-21ClinicalTrials.gov
NCT02439216EDASALONEXENTPHASE1/PHASE22022-09-23ClinicalTrials.gov
NCT01511900EDASALONEXENTPHASE1ClinicalTrials.gov

NIH grants 16891

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2422,025NIH's project files
P30CA008748Cancer Center Support Grant802,025NIH's project files
P30CA016058Cancer Center Support Grant572,025NIH's project files
P30ES001247Environmental Agents as Modulators of Disease Processes492,025NIH's project files
P30CA068485Cancer Center Support Grant482,025NIH's project files
P01CA125066Discovery of Anticancer Agents of Diverse Natural Origin422,025NIH's project files
R01CA097098Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer402,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award372,025NIH's project files
P30CA047904Cancer Center Support Grant362,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases362,025NIH's project files

Papers 50147

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822756PubTator, text miningPubMed
42820726PubTator, text miningPubMed
42820599PubTator, text miningPubMed
42818687PubTator, text miningPubMed
42817111PubTator, text miningPubMed
42816701PubTator, text miningPubMed
42815874PubTator, text miningPubMed
42813350PubTator, text miningPubMed
42812195PubTator, text miningPubMed
42812065PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license