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Gene · 5978

REST: RE1 silencing transcription factor

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. REST: RE1 silencing transcription factor. Genes, record 5978. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/5978

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
REST
HGNC
Name
RE1 silencing transcription factor
HGNC
NCBI Gene ID
5978
NCBI Gene
HGNC ID
HGNC:9966
HGNC
Ensembl
ENSG00000084093
NCBI Gene
Aliases
DFNA27, GINGF5, HGF5, NRSF, WT6, XBR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13127RE1-silencing transcription factor1,0973Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026511737 A2026-04-141Q13127Espacenet
EP 4692360 A12026-02-111Q13127Espacenet
JP 2026004568 A2026-01-1461118Q13127Espacenet
EP 4650780 A22025-11-194783Q13127Espacenet
EP 4641201 A22025-10-294352Q13127Espacenet
JP 2025147176 A2025-10-0615567Q13127Espacenet
JP 2025517969 A2025-06-124352Q13127Espacenet
JP 2025517970 A2025-06-124783Q13127Espacenet
JP 2025028160 A2025-02-2815567Q13127Espacenet
KR 1020250010750 A2025-01-2115567Q13127Espacenet

1 to 10 of 36

See all 36 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,592

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant242025
P30CA008748Cancer Center Support Grant202025
P50CA097186The Pacific Northwest Prostate Cancer SPORE142025
U24CA213274Coordinating center for the NCI small cell lung cancer research consortium102025
P30CA015704Cancer Center Support Grant92025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer82025
R37CA241486Molecular mechanisms underlying lineage plasticity in prostate cancer72025
ZIAAG000975ALZHEIMERS RESEARCH PROJECT / CLINICAL PROJECT: Mechanistic and clinical studies in Alzheimer's disease and related disorders72025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant62025
P01CA013106Targeting Transcription and Splicing in Cancer52025

1 to 10 of 3,592Source NIH's project files

See all 3,592 nih grants

Papers4,251

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827376PubTator, text miningPubMed
42696105PubTator, text miningPubMed
42639792PubTator, text miningPubMed
42613796PubTator, text miningPubMed
42608437PubTator, text miningPubMed
42530436PubTator, text miningPubMed
42486320PubTator, text miningPubMed
42423068PubTator, text miningPubMed
42400424PubTator, text miningPubMed
42395537PubTator, text miningPubMed

1 to 10 of 4,251

See all 4,251 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/5978

GET https://conductscience.org/api/genes/v1/5978/patents?page=2