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BCL2L1: BCL2 like 1

1 protein, 230 patents, 3 drugs, 55 trials, 12,562 NIH grants and 37,638 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBCL2L1HGNC
NameBCL2 like 1HGNC
NCBI Gene ID598NCBI Gene
HGNC IDHGNC:992HGNC
EnsemblENSG00000171552NCBI Gene
AliasesBCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52, bcl-xL, bcl-xSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q07817Bcl-2-like protein 1233126Ensembl, GeneID, HGNCUniProt

Patents 230

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0374Q07817Espacenet
JP 2025541604 A2025-12-2275Q07817Espacenet
JP 2025172069 A2025-11-20531Q07817Espacenet
JP 2025172069 A2025-11-20533Q07817Espacenet
EP 4650780 A22025-11-194149Q07817Espacenet
WO 2025229052 A12025-11-061Q07817Espacenet
EP 4641202 A22025-10-29213Q07817Espacenet
KR 1020250144510 A2025-10-1075Q07817Espacenet
JP 2025147176 A2025-10-0614721Q07817Espacenet
US 12419913 B22025-09-23239Q07817Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
NAVITOCLAXCHEMBL443684Apoptosis regulator Bcl-X inhibitorINHIBITORChEMBL
OBATOCLAXCHEMBL408194Apoptosis regulator Bcl-X inhibitorINHIBITORChEMBL
OBATOCLAX MESYLATECHEMBL2107358Apoptosis regulator Bcl-X inhibitorINHIBITORChEMBL

Trials 55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06210750NAVITOCLAXPHASE2ClinicalTrials.gov
NCT06007911NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05864742NAVITOCLAXPHASE2ClinicalTrials.gov
NCT05740449NAVITOCLAXPHASE1/PHASE2ClinicalTrials.gov
NCT05564650NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05455294NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05358639NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05222984NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05215405NAVITOCLAXClinicalTrials.gov
NCT05192889NAVITOCLAXPHASE1/PHASE22025-09-22ClinicalTrials.gov

NIH grants 12562

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant3842,025NIH's project files
P30CA008748Cancer Center Support Grant1182,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant682,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)572,025NIH's project files
P30CA047904Cancer Center Support Grant542,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant532,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028482,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant412,025NIH's project files
P50CA097190Head and Neck Cancer SPORE382,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant372,025NIH's project files

Papers 37638

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818383PubTator, text miningPubMed
42817838PubTator, text miningPubMed
42802426PubTator, text miningPubMed
42797376PubTator, text miningPubMed
42793017PubTator, text miningPubMed
42780598PubTator, text miningPubMed
42764286PubTator, text miningPubMed
42760649PubTator, text miningPubMed
42759759PubTator, text miningPubMed
42756215PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license