Gene · 5987
TRIM27: tripartite motif containing 27
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRIM27: tripartite motif containing 27. Genes, record 5987. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/5987
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14373 | Zinc finger protein RFP | 513 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents63
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68003 | P14373 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68004 | P14373 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68012 | P14373 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68013 | P14373 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68015 | P14373 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10155 | P14373 | Espacenet |
| WO 2025173787 A | 2025-08-21 | 12 | P14373 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10155 | P14373 | Espacenet |
| JP 2024161501 A | 2024-11-19 | 54 | P14373 | Espacenet |
| KR 1020240108531 A | 2024-07-09 | 54 | P14373 | Espacenet |
1 to 10 of 63
See all 63 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,792
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRIM27 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| T32CA121938 | UCSD Cancer Center Training Program in Drug Development | 6 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 4 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 4 | 2025 |
| R01DK073368 | Mechanisms of Compartmentalized cAMP Signaling | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,792Source NIH's project files
See all 1,792 nih grantsPapers2,241
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The Hao-Fountain syndrome gene USP7 restricts neurotropic orthoflavivirus entry through cell-intrinsic control of endosomal dynamics. | bioRxiv | 2026 | 42818731 | PubTator, text mining | PubMed |
| CRM1-Dependent Cytoplasmic Accumulation of TRIM27 Is Associated with Glomerular Endothelial Cell Injury in Lupus Nephritis. | Cells | 2026 | 42782796 | PubTator, text mining | PubMed |
| GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27-mediated ACLY Ubiquitination and Lipid Metabolism. | Adv Sci (Weinh) | 2026 | 42669779 | PubTator, text mining | PubMed |
| BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells. | Adv Sci (Weinh) | 2026 | 42593831 | PubTator, text mining | PubMed |
| TRIM27-Cas9-loaded EVs suppress HCC proliferation and enhance responsiveness to anti-PD-1 therapy by promoting ACSL4-mediated ferroptosis. | Cell Death Differ | 2026 | 42509343 | PubTator, text mining | PubMed |
| Machine Learning Models for Local Optimization of Red Fluorescent Protein Variants in a Low-Data Setting. | J Chem Inf Model | 2026 | 42443100 | PubTator, text mining | PubMed |
HMGB1 ubiquitination inhibition and extracellular secretion, mediated by m6A modified-exosomal lncRNA MALAT1, creates a communication between NK92-MI cells and tumor cells to aggravate acute lymphoblastic leukemia. | Cancer Immunol Immunother | 2026 | 42390539 | PubTator, text mining | PubMed |
| Integrating whole-genome bisulfite sequencing and TCGA data reveals methylation patterns associated with the MTHFR 677 C > T Variant. | Sci Rep | 2026 | 42373686 | PubTator, text mining | PubMed |
A novel oral vaccine strategy utilizing a plasmid with CAG promoter-driven alphavirus RdRp for Co-expression of NA epitope and adjuvant in attenuated Salmonella boosts immune responses against H9N2 in mice. | Microb Pathog | 2026 | 42297223 | PubTator, text mining | PubMed |
| Mechanisms of USP7/MAGEL2 Complex Assembly and Its Mutational Disruption in Neurodevelopmental Diseases. | bioRxiv | 2026 | 42094436 | PubTator, text mining | PubMed |
1 to 10 of 2,241
See all 2,241 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/5987
GET https://conductscience.org/api/genes/v1/5987/patents?page=2