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Gene · 599

BCL2L2: BCL2 like 2

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. BCL2L2: BCL2 like 2. Genes, record 599. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/599

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
BCL2L2
HGNC
Name
BCL2 like 2
HGNC
NCBI Gene ID
599
NCBI Gene
HGNC ID
HGNC:995
HGNC
Ensembl
ENSG00000129473
NCBI Gene
Aliases
BCL-W, BCL2-L-2, BCLW, KIAA0271, PPP1R51
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92843Bcl-2-like protein 21935Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191309Q92843Espacenet
JP 2025529142 A2025-09-04571Q92843Espacenet
US 12371689 B22025-07-29571Q92843Espacenet
JP 2025517970 A2025-06-121309Q92843Espacenet
JP 2025062604 A2025-04-148854Q92843Espacenet
JP 2024123008 A2024-09-105062Q92843Espacenet
US 11708396 B22023-07-251439Q92843Espacenet
US 11446398 B22022-09-208854Q92843Espacenet
JP 2022524081 A2022-04-27111825Q92843Espacenet
WO 2020043864 A12020-03-05281Q92843Espacenet

1 to 10 of 23

See all 23 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
NAVITOCLAXCHEMBL443684Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL
OBATOCLAXCHEMBL408194Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL
OBATOCLAX MESYLATECHEMBL2107358Apoptosis regulator Bcl-W inhibitorINHIBITORChEMBL

Trials55

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06210750NAVITOCLAXPHASE2ClinicalTrials.gov
NCT06007911NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05864742NAVITOCLAXPHASE2ClinicalTrials.gov
NCT05740449NAVITOCLAXPHASE1/PHASE2ClinicalTrials.gov
NCT05564650NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05455294NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05358639NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05222984NAVITOCLAXPHASE1ClinicalTrials.gov
NCT05215405NAVITOCLAXClinicalTrials.gov
NCT05192889NAVITOCLAXPHASE1/PHASE22025-09-22ClinicalTrials.gov

1 to 10 of 55

See all 55 trials

NIH grants1,985

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant302025
P30CA008748Cancer Center Support Grant202025
P30CA021765Cancer Center Support Grant (CCSG)162025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant132025
P30CA046934University of Colorado Cancer Center Support Grant112025
P30CA030199Cancer Center Support Grant (CCSG)92025
P30CA076292Moffitt Cancer Center Support Grant92025
R37AG013925Effect of Aging on Preadipocyte Differentiation92025
P01AG062413Targeting Cellular Senescence to Extend Healthspan82025
P30CA016059Massey Cancer Center - Cancer Center Support Grant82025

1 to 10 of 1,985Source NIH's project files

See all 1,985 nih grants

Papers4,142

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42730969PubTator, text miningPubMed
42488690PubTator, text miningPubMed
42424099PubTator, text miningPubMed
42400794PubTator, text miningPubMed
42397105PubTator, text miningPubMed
42379883PubTator, text miningPubMed
42297746PubTator, text miningPubMed
42236666PubTator, text miningPubMed
42167518PubTator, text miningPubMed
42099139PubTator, text miningPubMed

1 to 10 of 4,142

See all 4,142 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/599

GET https://conductscience.org/api/genes/v1/599/patents?page=2