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Gene · 6009

RHEB: Ras homolog, mTORC1 binding

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. RHEB: Ras homolog, mTORC1 binding. Genes, record 6009. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/6009

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
RHEB
HGNC
Name
Ras homolog, mTORC1 binding
HGNC
NCBI Gene ID
6009
NCBI Gene
HGNC ID
HGNC:10011
HGNC
Ensembl
ENSG00000106615
NCBI Gene
Aliases
RHEB2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15382GTP-binding protein Rheb18415Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-094Q15382Espacenet
EP 4650780 A22025-11-192028Q15382Espacenet
JP 2025517970 A2025-06-122028Q15382Espacenet
JP 2025032204 A2025-03-1134839Q15382Espacenet
EP 4461818 A22024-11-1334839Q15382Espacenet
JP 2024123008 A2024-09-108107Q15382Espacenet
JP 2023058610 A2023-04-2534839Q15382Espacenet
US 11612641 B22023-03-282Q15382Espacenet
US 11446398 B22022-09-2071784Q15382Espacenet
JP 2022524081 A2022-04-27174755Q15382Espacenet

1 to 10 of 57

See all 57 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,011

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes532025
P30CA016672Cancer Center Support Grant342025
P30CA008748Cancer Center Support Grant302025
ZIAHL002541Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)152025
P30DK020572Michigan Diabetes Research Center (MDRC)122025
P30CA010815Consolidated Basic Cancer Research Program82025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)82025
P50CA101942DF/HCC Kidney Cancer SPORE (supplement)82025
R01CA109182Functional Determinants of Metastatic Dormancy82025

1 to 10 of 3,011Source NIH's project files

See all 3,011 nih grants

Papers4,441

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42691045PubTator, text miningPubMed
42670563PubTator, text miningPubMed
42583078PubTator, text miningPubMed
42566506PubTator, text miningPubMed
42509683PubTator, text miningPubMed
42505822PubTator, text miningPubMed
42386939PubTator, text miningPubMed
42259854PubTator, text miningPubMed
42257688PubTator, text miningPubMed
42232606PubTator, text miningPubMed

1 to 10 of 4,441

See all 4,441 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

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