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Gene · 60485

SAV1: salvador family WW domain containing protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SAV1: salvador family WW domain containing protein 1. Genes, record 60485. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/60485

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Gene

Symbol
SAV1
HGNC
Name
salvador family WW domain containing protein 1
HGNC
NCBI Gene ID
60485
NCBI Gene
HGNC ID
HGNC:17795
HGNC
Ensembl
ENSG00000151748
NCBI Gene
Aliases
SAV, WW45, WWP4, salvador
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9H4B6Protein salvador homolog 13831Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195567Q9H4B6Espacenet
JP 2025517970 A2025-06-125567Q9H4B6Espacenet
US 11564998 B22023-01-315478Q9H4B6Espacenet
US 11446398 B22022-09-2076391Q9H4B6Espacenet
JP 2022524081 A2022-04-27179362Q9H4B6Espacenet
US 11078247 B22021-08-039948Q9H4B6Espacenet
US 10463751 B22019-11-055478Q9H4B6Espacenet
JP 2018023373 A2018-02-1528205Q9H4B6Espacenet
US 9572897 B22017-02-215478Q9H4B6Espacenet
US 9303079 B22016-04-055478Q9H4B6Espacenet

1 to 10 of 30

See all 30 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants964

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSAV1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant302025
R01EY015708Control of Cell Number in Developing Retina112025
R01GM126048Regulation and function of the Hippo pathway in growth control52025
R01HL118761Pitx2 in atrial fibrillation52025
P30CA008748Cancer Center Support Grant42025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant42025
P30DK026743UCSF Liver Center42025
R01NS034783Function of NF2/Merlin in regulation of the Hippo/Salvador/Warts growth control pathway42025
T32CA009110Training in Areas Fundamental to Cancer Research42025
T32DK007028Training Program in Endocrinology42025

1 to 10 of 964Source NIH's project files

See all 964 nih grants

Papers1,483

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Hippo-YAP/TAZ signaling in gastric cancer: orchestrating epithelial-stromal heterogeneity, plasticity, and therapy resistance.Cancer Heterog Plast202642770147PubTator, text miningPubMed
SAV1 in Cooperation With FKBP52 Participates in Implantation.Adv Sci (Weinh)202642750339PubTator, text miningPubMed
Role of Phase Separation in Hippo Pathway Regulation.Cold Spring Harb Perspect Biol202642674838PubTator, text miningPubMed
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
Circulating NSUN6 serves as a prognostic biomarker for early metastasis in HCC via hippo pathway modulation.J Exp Clin Cancer Res202642464346PubTator, text miningPubMed
The Plant Hippo Pathway: An Evolved Hub for Strategic Resource Allocation Governing Growth-Defence-Reproduction Trade-Offs.Plant Cell Environ202642449547PubTator, text miningPubMed
TEAD1 condensates are transcriptionally inactive storage sites on the pericentromeric heterochromatin in cancer cells.Nat Cell Biol202642277434PubTator, text miningPubMed
Structural Studies of Core Hippo Pathway Components.Cold Spring Harb Perspect Biol202642150850PubTator, text miningPubMed
TIAL1 regulates the Hippo pathway through an RNA-binding-independent mechanism.Oncogene202642032365PubTator, text miningPubMed
OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma.Cell Death Dis202641951612PubTator, text miningPubMed

1 to 10 of 1,483

See all 1,483 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/60485

GET https://conductscience.org/api/genes/v1/60485/patents?page=2