Gene · 60485
SAV1: salvador family WW domain containing protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SAV1: salvador family WW domain containing protein 1. Genes, record 60485. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/60485
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9H4B6 | Protein salvador homolog 1 | 383 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents30
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 5567 | Q9H4B6 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5567 | Q9H4B6 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 5478 | Q9H4B6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 76391 | Q9H4B6 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 179362 | Q9H4B6 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 9948 | Q9H4B6 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 5478 | Q9H4B6 | Espacenet |
| JP 2018023373 A | 2018-02-15 | 28205 | Q9H4B6 | Espacenet |
| US 9572897 B2 | 2017-02-21 | 5478 | Q9H4B6 | Espacenet |
| US 9303079 B2 | 2016-04-05 | 5478 | Q9H4B6 | Espacenet |
1 to 10 of 30
See all 30 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants964
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SAV1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 30 | 2025 |
| R01EY015708 | Control of Cell Number in Developing Retina | 11 | 2025 |
| R01GM126048 | Regulation and function of the Hippo pathway in growth control | 5 | 2025 |
| R01HL118761 | Pitx2 in atrial fibrillation | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| P30DK026743 | UCSF Liver Center | 4 | 2025 |
| R01NS034783 | Function of NF2/Merlin in regulation of the Hippo/Salvador/Warts growth control pathway | 4 | 2025 |
| T32CA009110 | Training in Areas Fundamental to Cancer Research | 4 | 2025 |
| T32DK007028 | Training Program in Endocrinology | 4 | 2025 |
1 to 10 of 964Source NIH's project files
See all 964 nih grantsPapers1,483
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Hippo-YAP/TAZ signaling in gastric cancer: orchestrating epithelial-stromal heterogeneity, plasticity, and therapy resistance. | Cancer Heterog Plast | 2026 | 42770147 | PubTator, text mining | PubMed |
| SAV1 in Cooperation With FKBP52 Participates in Implantation. | Adv Sci (Weinh) | 2026 | 42750339 | PubTator, text mining | PubMed |
| Role of Phase Separation in Hippo Pathway Regulation. | Cold Spring Harb Perspect Biol | 2026 | 42674838 | PubTator, text mining | PubMed |
| Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output. | Cold Spring Harb Perspect Biol | 2026 | 42575696 | PubTator, text mining | PubMed |
| Circulating NSUN6 serves as a prognostic biomarker for early metastasis in HCC via hippo pathway modulation. | J Exp Clin Cancer Res | 2026 | 42464346 | PubTator, text mining | PubMed |
| The Plant Hippo Pathway: An Evolved Hub for Strategic Resource Allocation Governing Growth-Defence-Reproduction Trade-Offs. | Plant Cell Environ | 2026 | 42449547 | PubTator, text mining | PubMed |
| TEAD1 condensates are transcriptionally inactive storage sites on the pericentromeric heterochromatin in cancer cells. | Nat Cell Biol | 2026 | 42277434 | PubTator, text mining | PubMed |
| Structural Studies of Core Hippo Pathway Components. | Cold Spring Harb Perspect Biol | 2026 | 42150850 | PubTator, text mining | PubMed |
| TIAL1 regulates the Hippo pathway through an RNA-binding-independent mechanism. | Oncogene | 2026 | 42032365 | PubTator, text mining | PubMed |
| OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma. | Cell Death Dis | 2026 | 41951612 | PubTator, text mining | PubMed |
1 to 10 of 1,483
See all 1,483 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/60485
GET https://conductscience.org/api/genes/v1/60485/patents?page=2