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Gene · 60489

APOBEC3G: apolipoprotein B mRNA editing enzyme catalytic subunit 3G

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. APOBEC3G: apolipoprotein B mRNA editing enzyme catalytic subunit 3G. Genes, record 60489. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/60489

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Gene

Symbol
APOBEC3G
HGNC
Name
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
HGNC
NCBI Gene ID
60489
NCBI Gene
HGNC ID
HGNC:17357
HGNC
Ensembl
ENSG00000239713
NCBI Gene
Aliases
A3G, ARCD, ARP-9, ARP9, CEM-15, CEM15, FLJ12740, MDS019, bK150C2.7, dJ494G10.1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9HC16DNA dC->dU-editing enzyme APOBEC-3G38422Ensembl, GeneID, HGNC

Source UniProt

Patents244

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4828972 A12026-10-2836Q9HC16Espacenet
EP 4828972 A12026-10-28583Q9HC16Espacenet
EP 4828972 A12026-10-28629Q9HC16Espacenet
JP 2026525611 A2026-07-3168Q9HC16Espacenet
JP 2026525612 A2026-07-31501Q9HC16Espacenet
EP 4777618 A12026-07-2236Q9HC16Espacenet
EP 4777618 A12026-07-22583Q9HC16Espacenet
EP 4777618 A12026-07-22629Q9HC16Espacenet
JP 2026116287 A2026-07-09272Q9HC16Espacenet
EP 4762095 A12026-06-2436Q9HC16Espacenet

1 to 10 of 244

See all 244 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,647

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPOBEC3G papersNewest fiscal year
P30AI027763UCSF-Bay Area Center for AIDS Research412025
ZIAAI000669Molecular Analysis Of Retroviral Genes And Their Products352025
T32AI083196Minnesota Training Program in Virology312025
ZIABC010595Structure and Function of Vif and APOBEC3 (A3) Proteins252025
P01CA234228APOBEC Mutagenesis in Cancer232025
T32CA009138Molecular, Genetic and Cellular Targets of Cancer Training Program202025
P30AI094189The Johns Hopkins Center for AIDS Research (JHU CFAR)192025
P30AI060354Harvard University Center for AIDS Research142025
ZIABC010504Understanding Retroviral Reverse Transcription, Recombination, and Replication122025
P30CA008748Cancer Center Support Grant112025

1 to 10 of 2,647Source NIH's project files

See all 2,647 nih grants

Papers3,812

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Structural Adaptability in HIV-2 Vif Drives Broad Antagonism of APOBEC3G.bioRxiv202642818250PubTator, text miningPubMed
Deubiquitinase USP8 inhibits HIV-1 replication by suppressing Tat-mediated viral transactivation.J Virol202642803586PubTator, text miningPubMed
Multiscale Transcriptomic and Molecular Modeling Analyses Suggest DCPMU-Associated Epithelial Remodeling and Tumor Microenvironment Perturbation in Prostate Cancer.Curr Issues Mol Biol202642793291PubTator, text miningPubMed
Engineered Transformer Base Editor with Enhanced Editing Efficiency.Adv Sci (Weinh)202642723179PubTator, text miningPubMed
The Innate Antiviral Factors APOBEC3G and APOBEC3H Interact with the Nucleocapsids of Human Coronaviruses in an RNA-Dependent Manner.Viruses202642655650PubTator, text miningPubMed
Structural Basis of Intermolecular Interactions Between APOBEC3 and HIV-1 Vif.Viruses202642515639PubTator, text miningPubMed
Strain-specific epistasis shapes fitness landscapes of APOBEC3G antagonism by HIV-1 Vif proteins.Sci Adv202642490454PubTator, text miningPubMed
Integrated immune profiling identifies a coordinated T-cell activation and inflammatory signature in SLE.Lupus Sci Med202642457337PubTator, text miningPubMed
Human APOBEC3G suppresses homologous recombination and LIG4-independent end joining in DNA double-strand break repair.FEBS J202642403051PubTator, text miningPubMed
Full-length structure of the anti-viral and pro-tumor DNA deaminase APOBEC3B.bioRxiv202642367898PubTator, text miningPubMed

1 to 10 of 3,812

See all 3,812 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/60489

GET https://conductscience.org/api/genes/v1/60489/patents?page=2