ConductScience.org, home

Gene · 6091

ROBO1: roundabout guidance receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ROBO1: roundabout guidance receptor 1. Genes, record 6091. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6091

On this page

Gene

Symbol
ROBO1
HGNC
Name
roundabout guidance receptor 1
HGNC
NCBI Gene ID
6091
NCBI Gene
HGNC ID
HGNC:10249
HGNC
Ensembl
ENSG00000169855
NCBI Gene
Aliases
CPHD8, DUTT1, FLJ21882, NORS, NYS8, SAX3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y6N7Roundabout homolog 11,65112Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462463Q9Y6N7Espacenet
EP 4650780 A22025-11-1914422Q9Y6N7Espacenet
EP 4641201 A22025-10-2916897Q9Y6N7Espacenet
JP 2025529142 A2025-09-043762Q9Y6N7Espacenet
US 12371689 B22025-07-293762Q9Y6N7Espacenet
JP 2025517969 A2025-06-1216897Q9Y6N7Espacenet
JP 2025517970 A2025-06-1214422Q9Y6N7Espacenet
EP 4527406 A12025-03-2683Q9Y6N7Espacenet
WO 2023224096 A2023-11-2383Q9Y6N7Espacenet
JP 2023530489 A2023-07-186Q9Y6N7Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,710

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleROBO1 papersNewest fiscal year
P50HD027802Differential Diagnosis in Learning Disabilities122025
P30CA016672Cancer Center Support Grant92025
UL1TR001863Yale Clinical and Translational Science Award82025
P50HD052120Learning Disabilities Translational Science Collective: Building on the Florida LDRC72025
P30CA068485Cancer Center Support Grant52025
P30CA014051Cancer Center Support (Core) Grant42025
P30CA016058Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025
P30EY014801Miami Center for Vision Research42025
P40OD010440Caenorhabditis Genetics Center42025

1 to 10 of 1,710Source NIH's project files

See all 1,710 nih grants

Papers2,184

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Evolution of NELL binding by dual-ligand-responsive axon guidance receptor Robo.bioRxiv202642818381PubTator, text miningPubMed
Genomic spectrum of congenital heart disease combined with kidney and urinary tract anomalies uncovered by exome sequencing and array-CGH.Front Cell Dev Biol202642780563PubTator, text miningPubMed
Clinical and Genetic Analysis of Pediatric Neurodevelopmental Disorders With Complex Chromosomal Rearrangements in Two Cases.Mol Genet Genomic Med202642773581PubTator, text miningPubMed
Gbx2 and Robo receptors control amacrine cell dendrite stratification in the mammalian retina.Dev Biol202642716364PubTator, text miningPubMed
Druggable tumor-nerve-immune circuits in cancer pain: Model systems, human translatability and therapeutic paradoxes.Pharmacol Res202642716238PubTator, text miningPubMed
Epicardial adipose tissue-secreted ANGPTL2 drives obesity-induced atrial fibrosis via the SLIT3/ROBO1 and Wnt5a signaling axes.Cell Signal202642600716PubTator, text miningPubMed
Membrane proteomic profiling to identify candidate therapy targets for glioblastoma infiltration.Neurooncol Adv202642534387PubTator, text miningPubMed
Genome-Wide and Rare Variant Association Studies of Amblyopia in Admixed American and African Ancestry Groups.Ophthalmology202642508771PubTator, text miningPubMed
Repression of ROBO1 Enhances Cisplatin Sensitivity in Hypermethylated Subtype of HPV-Positive Head and Neck Carcinoma.Cancer Sci202642463168PubTator, text miningPubMed
A novel circSLIT2-encoded SLIT2 isoform suppresses neural invasion in gastric cancer.Oncogene202642362756PubTator, text miningPubMed

1 to 10 of 2,184

See all 2,184 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6091

GET https://conductscience.org/api/genes/v1/6091/patents?page=2