Gene · 6091
ROBO1: roundabout guidance receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ROBO1: roundabout guidance receptor 1. Genes, record 6091. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6091
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y6N7 | Roundabout homolog 1 | 1,651 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 62463 | Q9Y6N7 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 14422 | Q9Y6N7 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 16897 | Q9Y6N7 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 3762 | Q9Y6N7 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 3762 | Q9Y6N7 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 16897 | Q9Y6N7 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 14422 | Q9Y6N7 | Espacenet |
| EP 4527406 A1 | 2025-03-26 | 83 | Q9Y6N7 | Espacenet |
| WO 2023224096 A | 2023-11-23 | 83 | Q9Y6N7 | Espacenet |
| JP 2023530489 A | 2023-07-18 | 6 | Q9Y6N7 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,710
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ROBO1 papers | Newest fiscal year |
|---|---|---|---|
| P50HD027802 | Differential Diagnosis in Learning Disabilities | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 8 | 2025 |
| P50HD052120 | Learning Disabilities Translational Science Collective: Building on the Florida LDRC | 7 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 4 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 4 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 4 | 2025 |
1 to 10 of 1,710Source NIH's project files
See all 1,710 nih grantsPapers2,184
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Evolution of NELL binding by dual-ligand-responsive axon guidance receptor Robo. | bioRxiv | 2026 | 42818381 | PubTator, text mining | PubMed |
| Genomic spectrum of congenital heart disease combined with kidney and urinary tract anomalies uncovered by exome sequencing and array-CGH. | Front Cell Dev Biol | 2026 | 42780563 | PubTator, text mining | PubMed |
| Clinical and Genetic Analysis of Pediatric Neurodevelopmental Disorders With Complex Chromosomal Rearrangements in Two Cases. | Mol Genet Genomic Med | 2026 | 42773581 | PubTator, text mining | PubMed |
| Gbx2 and Robo receptors control amacrine cell dendrite stratification in the mammalian retina. | Dev Biol | 2026 | 42716364 | PubTator, text mining | PubMed |
| Druggable tumor-nerve-immune circuits in cancer pain: Model systems, human translatability and therapeutic paradoxes. | Pharmacol Res | 2026 | 42716238 | PubTator, text mining | PubMed |
| Epicardial adipose tissue-secreted ANGPTL2 drives obesity-induced atrial fibrosis via the SLIT3/ROBO1 and Wnt5a signaling axes. | Cell Signal | 2026 | 42600716 | PubTator, text mining | PubMed |
| Membrane proteomic profiling to identify candidate therapy targets for glioblastoma infiltration. | Neurooncol Adv | 2026 | 42534387 | PubTator, text mining | PubMed |
| Genome-Wide and Rare Variant Association Studies of Amblyopia in Admixed American and African Ancestry Groups. | Ophthalmology | 2026 | 42508771 | PubTator, text mining | PubMed |
| Repression of ROBO1 Enhances Cisplatin Sensitivity in Hypermethylated Subtype of HPV-Positive Head and Neck Carcinoma. | Cancer Sci | 2026 | 42463168 | PubTator, text mining | PubMed |
| A novel circSLIT2-encoded SLIT2 isoform suppresses neural invasion in gastric cancer. | Oncogene | 2026 | 42362756 | PubTator, text mining | PubMed |
1 to 10 of 2,184
See all 2,184 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6091
GET https://conductscience.org/api/genes/v1/6091/patents?page=2