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RORC: RAR related orphan receptor C

1 protein, 52 patents, 1 drug, 0 trials, 4,496 NIH grants and 6,963 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRORCHGNC
NameRAR related orphan receptor CHGNC
NCBI Gene ID6097NCBI Gene
HGNC IDHGNC:10260HGNC
EnsemblENSG00000143365NCBI Gene
AliasesIMD42, NR1F3, RORG, RZR-GAMMA, RZRG, TORNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P51449Nuclear receptor ROR-gamma518162Ensembl, GeneID, HGNCUniProt

Patents 52

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026120675 A2026-07-22767P51449Espacenet
JP 2026086503 A2026-05-2686P51449Espacenet
JP 2026505362 A2026-02-1313P51449Espacenet
JP 2026004568 A2026-01-1460978P51449Espacenet
EP 4661884 A22025-12-1713P51449Espacenet
EP 4640849 A22025-10-29819P51449Espacenet
EP 4641201 A22025-10-295355P51449Espacenet
EP 4641202 A22025-10-294996P51449Espacenet
JP 2025147176 A2025-10-0615585P51449Espacenet
JP 2025519096 A2025-06-24819P51449Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
JTE-151CHEMBL3545357Nuclear receptor ROR-gamma antagonistANTAGONISTChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4496

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAES101586Nuclear receptors: action, functions, and roles in disease282,025NIH's project files
P30CA008748Cancer Center Support Grant192,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases182,025NIH's project files
P30CA016087Cancer Center Support Grant162,025NIH's project files
P01AI039671Costimulatory Mechanisms of Autoimmunity152,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success152,025NIH's project files
R01AI127564Genome-wide search for inborn errors of IL-17 immunity underlying chronic mucocutaneous candidiasis142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged122,025NIH's project files

Papers 6963

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826173PubTator, text miningPubMed
42763003PubTator, text miningPubMed
42695969PubTator, text miningPubMed
42685456PubTator, text miningPubMed
42628146PubTator, text miningPubMed
42616895PubTator, text miningPubMed
42614016PubTator, text miningPubMed
42607655PubTator, text miningPubMed
42583130PubTator, text miningPubMed
42577896PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license