ConductScience.org, home

Library / Genes

RPA1: replication protein A1

1 protein, 71 patents, 0 drugs, 0 trials, 5,753 NIH grants and 9,932 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolRPA1HGNC
Namereplication protein A1HGNC
NCBI Gene ID6117NCBI Gene
HGNC IDHGNC:10289HGNC
EnsemblENSG00000132383NCBI Gene
AliasesHSSB, MST075, PFBMFT6, REPA1, RF-A, RP-A, RPA70NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P27694Replication protein A 70 kDa DNA-binding subunit61642Ensembl, GeneID, HGNCUniProt

Patents 71

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4791890 A22026-08-19118P27694Espacenet
JP 2026009871 A2026-01-21140P27694Espacenet
JP 2025100656 A2025-07-0320P27694Espacenet
WO 2025132779 A22025-06-267P27694Espacenet
WO 2025132780 A22025-06-267P27694Espacenet
WO 2025137293 A22025-06-2611P27694Espacenet
US 12281338 B22025-04-2266P27694Espacenet
JP 2025032204 A2025-03-1134991P27694Espacenet
EP 4461818 A22024-11-1334991P27694Espacenet
JP 2024123008 A2024-09-108166P27694Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5753

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P01CA092584Structural Cell Biology of DNA Repair Machines1572,025NIH's project files
P30CA008748Cancer Center Support Grant652,025NIH's project files
P30CA016672Cancer Center Support Grant612,025NIH's project files
ZIAAG000741Roles Of DNA Helicases In Pathways Required For Maintenance Of Genomic Stability432,025NIH's project files
R01ES007061Mechanisms of DNA Double-strand Break End Resection and Repair Pathway Choice342,025NIH's project files
P30CA086862Cancer Center Support Grant312,025NIH's project files
P30CA068485Cancer Center Support Grant302,025NIH's project files
ZIAAG000753Fanconi Anemia Pathway292,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility282,025NIH's project files
R01GM058015Recombinational Mechanisms of DNA Repair252,025NIH's project files

Papers 9932

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822416PubTator, text miningPubMed
42794475PubTator, text miningPubMed
42792682PubTator, text miningPubMed
42779690PubTator, text miningPubMed
42773178PubTator, text miningPubMed
42767448PubTator, text miningPubMed
42715083PubTator, text miningPubMed
42709834PubTator, text miningPubMed
42661818PubTator, text miningPubMed
42655845PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license