ConductScience.org, home

Gene · 6135

RPL11: ribosomal protein L11

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RPL11: ribosomal protein L11. Genes, record 6135. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6135

On this page

Gene

Symbol
RPL11
HGNC
Name
ribosomal protein L11
HGNC
NCBI Gene ID
6135
NCBI Gene
HGNC ID
HGNC:10301
HGNC
Ensembl
ENSG00000142676
NCBI Gene
Aliases
DBA7, GIG34, L11, uL5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62913Large ribosomal subunit protein uL5178168Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461972P62913Espacenet
EP 4641202 A22025-10-299823P62913Espacenet
KR 1020250017231 A2025-02-049823P62913Espacenet
WO 2024240908 A12024-11-2836P62913Espacenet
JP 2022165557 A2022-11-019P62913Espacenet
US 11446398 B22022-09-2073929P62913Espacenet
JP 2022524081 A2022-04-27176900P62913Espacenet
WO 2020043864 A12020-03-052113P62913Espacenet
JP 2019054813 A2019-04-11242407P62913Espacenet
JP 2018036233 A2018-03-0811P62913Espacenet

1 to 10 of 28

See all 28 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants1,187

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL11 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
P30CA016672Cancer Center Support Grant82025
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes72025
P01CA163222Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment42025
P30CA016086Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202842025
R01AR043369MITF from control of pigmentation to melanoma risk42025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis42025
P30CA010815Consolidated Basic Cancer Research Program32025

1 to 10 of 1,187Source NIH's project files

See all 1,187 nih grants

Papers1,885

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Ribosomal Protein L11 Mediates Antiviral Defense via Activation of Apoptosis in Bombyx mori.J Agric Food Chem202642677657PubTator, text miningPubMed
MYC-driven BYSL overexpression promotes hepatocellular carcinoma by suppressing nucleolar stress and inactivating the RPL5/RPL11-MDM2-p53 pathway.Cell Signal202642575394PubTator, text miningPubMed
RPS5 modulates inflammatory response and angiogenesis in coronary heart disease through NF-κB signaling activation.Mol Cell Biochem202642440233PubTator, text miningPubMed
KDM4D enhances radiosensitivity in esophageal squamous cell carcinoma through the SRBD1/RPL11/c-Myc/WIP1/CHK1 axis.Am J Transl Res202642325777PubTator, text miningPubMed
Structural Insights into the Cyclic Peptide Antibiotic Thiostrepton via NMR Spectroscopy.J Phys Chem A202642299055PubTator, text miningPubMed
Integrative transcriptomic and systems biology analysis of public SLE datasets identifies immune regulatory pathways.J Comput Aided Mol Des202642295464PubTator, text miningPubMed
Mutant KRAS-driven selective mRNA translation reveals mechanisms and therapeutic vulnerabilities in cancer.Cell Rep202642284146PubTator, text miningPubMed
MAZ-driven MRPL11 links mitochondrial homeostasis to AKT/mTOR signaling and promotes pancreatic ductal adenocarcinoma progression.Biochim Biophys Acta Mol Basis Dis202642263886PubTator, text miningPubMed
A RiboCancer cell line panel reveals that CLL-associated Rps15 mutations translationally rewire transcription through codon-specific tRNA accommodation defects.Hemasphere202642255948PubTator, text miningPubMed
Single-cell transcriptomics and machine learning unveil liquid-liquid phase separation-related biomarkers in HPV-positive cervical cancer.Infect Agent Cancer202642251432PubTator, text miningPubMed

1 to 10 of 1,885

See all 1,885 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6135

GET https://conductscience.org/api/genes/v1/6135/patents?page=2