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Gene · 6138

RPL15: ribosomal protein L15

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL15: ribosomal protein L15. Genes, record 6138. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6138

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Gene

Symbol
RPL15
HGNC
Name
ribosomal protein L15
HGNC
NCBI Gene ID
6138
NCBI Gene
HGNC ID
HGNC:10306
HGNC
Ensembl
ENSG00000174748
NCBI Gene
Aliases
DBA12, EC45, L15, RPL10, RPLY10, RPYL10, eL15
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61313Large ribosomal subunit protein eL15204175Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461980P61313Espacenet
JP 2026004568 A2026-01-1461981P61313Espacenet
JP 2026004568 A2026-01-1461983P61313Espacenet
JP 2026004568 A2026-01-1461984P61313Espacenet
JP 2026004568 A2026-01-1461987P61313Espacenet
EP 4650780 A22025-11-194611P61313Espacenet
EP 4641202 A22025-10-294846P61313Espacenet
JP 2025517970 A2025-06-124611P61313Espacenet
KR 1020250017231 A2025-02-044846P61313Espacenet
US 11446398 B22022-09-2073951P61313Espacenet

1 to 10 of 61

See all 61 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants677

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL15 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA072720Cancer Center Support Grant32025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis32025
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease32025
K12CA087723Dana Farber/Harvard Cancer Consortium Career Development Program in Clinical Oncology22025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.22025
P20GM121293Center for Translational Pediatric Research22025

1 to 10 of 677Source NIH's project files

See all 677 nih grants

Papers806

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-cell transcriptomics combined with Mendelian randomization reveals the pivotal role of WDR83OS in clear cell renal cell carcinoma: An observational and bioinformatic study.Medicine (Baltimore)202642760660PubTator, text miningPubMed
The loss of function of a C2H2 zinc finger protein alleviates its inhibitory effect on LsRPL15, causing dense red spots in lettuce.Plant Physiol202642612177PubTator, text miningPubMed
Fully Complementary Interactions Between LmiRNA and mRNA of Human Genes.Curr Issues Mol Biol202642510906PubTator, text miningPubMed
Association between omeprazole and memory impairment: Insights from NHANES data analysis and network pharmacology studies.J Alzheimers Dis202641879275PubTator, text miningPubMed
Maternal opioid use disorder and hepatitis C infection in pregnancy reshape the peripheral immune landscape at term.EBioMedicine202641849830PubTator, text miningPubMed
Neurons with granulovacuolar degeneration bodies are resilient to tau-induced protein synthesis impairment.Sci Adv202641790889PubTator, text miningPubMed
Identification of multigene predictors of prognosis in patients with ovarian cancer.iScience202641767263PubTator, text miningPubMed
Decoding the role of RPL38 in lung adenocarcinoma: a multi-omics approach.Front Immunol202641766901PubTator, text miningPubMed
PROTAC-based protein degradation: a window of opportunity for melanoma therapy.J Biomed Sci202641761284PubTator, text miningPubMed
Tissue-Specific Multi-Omics Integration Demonstrates Molecular Signatures Connecting Obesity to Immune Vulnerability.Metabolites202641745578PubTator, text miningPubMed

1 to 10 of 806

See all 806 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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