ConductScience.org, home

Gene · 6141

RPL18: ribosomal protein L18

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RPL18: ribosomal protein L18. Genes, record 6141. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6141

On this page

Gene

Symbol
RPL18
HGNC
Name
ribosomal protein L18
HGNC
NCBI Gene ID
6141
NCBI Gene
HGNC ID
HGNC:10310
HGNC
Ensembl
ENSG00000063177
NCBI Gene
Aliases
DBA18, L18, eL18
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q07020Large ribosomal subunit protein eL18188179Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461996Q07020Espacenet
EP 4650780 A22025-11-1916471Q07020Espacenet
EP 4641202 A22025-10-298129Q07020Espacenet
JP 2025517970 A2025-06-1216471Q07020Espacenet
KR 1020250017231 A2025-02-048129Q07020Espacenet
US 11446398 B22022-09-2073979Q07020Espacenet
JP 2022524081 A2022-04-27176950Q07020Espacenet
US 11078247 B22021-08-039751Q07020Espacenet
WO 2020043864 A12020-03-052118Q07020Espacenet
JP 2019054813 A2019-04-11242431Q07020Espacenet

1 to 10 of 30

See all 30 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants665

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL18 papersNewest fiscal year
P30CA008748Cancer Center Support Grant32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA016086Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center22025
P30DK063491Diabetes Research Center (DRC)22025
P50CA116201Mayo Clinic Breast Cancer SPORE22025
P50CA196516University of Texas Southwestern Medical Center SPORE in Kidney Cancer22025

1 to 10 of 665Source NIH's project files

See all 665 nih grants

Papers831

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins.J Microsc Ultrastruct202642824931PubTator, text miningPubMed
TRIM21-Mediated ubiquitination of FBL suppresses PI3K/AKT signaling and tumor progression in clear cell renal cell carcinoma.Cell Mol Life Sci202641863623PubTator, text miningPubMed
A three generation family with VACTERL association is found to have a rare form of diamond-blackfan anaemia.Eur J Hum Genet202641851260PubTator, text miningPubMed
Pairing taguchi based design of experiment with response surface methodology for diesel engine performance optimization using biodiesel-magnesium oxide nanoparticles blends.PLoS One202641779812PubTator, text miningPubMed
Manganese modulates hepatocellular carcinoma cytotoxicity and doxorubicin sensitivity in a dose dependent manner.Front Oncol202641768239PubTator, text miningPubMed
Radiomics predicts poorly differentiated hepatocellular carcinoma and uncovers ribosomal-immune dysregulation mechanism.iScience202641732485PubTator, text miningPubMed
Bioreactor expansion of human neural progenitor cells for exosome scalable production and miRNA-engineering.J Biol Eng202641715202PubTator, text miningPubMed
ENY2 transcription and export complex 2 subunit deficiency induces nucleolar stress to inhibit tumor progression through NPM1/MDM2/p53-dependent and -independent responses.Cell Oncol (Dordr)202641642454PubTator, text miningPubMed
Validation of Stable Reference Genes for RT-qPCR Normalization in Oxycetonia jucunda (Coleoptera: Scarabaeidae).Insects202641598911PubTator, text miningPubMed
Exploring molecular signatures in PURA syndrome using muscle proteomics and serum biomarkers.J Neurol202641575592PubTator, text miningPubMed

1 to 10 of 831

See all 831 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6141

GET https://conductscience.org/api/genes/v1/6141/patents?page=2