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Gene · 6142

RPL18A: ribosomal protein L18a

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL18A: ribosomal protein L18a. Genes, record 6142. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6142

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Gene

Symbol
RPL18A
HGNC
Name
ribosomal protein L18a
HGNC
NCBI Gene ID
6142
NCBI Gene
HGNC ID
HGNC:10311
HGNC
Ensembl
ENSG00000105640
NCBI Gene
Aliases
L18A, eL20
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q02543Large ribosomal subunit protein eL20176177Ensembl, GeneID, HGNC

Source UniProt

Patents27

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461998Q02543Espacenet
EP 4650780 A22025-11-19543Q02543Espacenet
JP 2025517970 A2025-06-12543Q02543Espacenet
US 11446398 B22022-09-2073986Q02543Espacenet
JP 2022524081 A2022-04-27176957Q02543Espacenet
WO 2020043864 A12020-03-052119Q02543Espacenet
JP 2019054813 A2019-04-11242433Q02543Espacenet
JP 2017197443 A2017-11-0262Q02543Espacenet
JP 2017121241 A2017-07-13242433Q02543Espacenet
JP 2015516143 A2015-06-08242433Q02543Espacenet

1 to 10 of 27

See all 27 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants415

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL18A papersNewest fiscal year
P01CA100730Retrovirus Models of Cancer32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA015704Cancer Center Support Grant22025
P30CA016058Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P30DK034854Integrated Epithelial and Muscosal Biology22025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens12025
P30AI050409Center for AIDS Research at Emory University12025

1 to 10 of 415Source NIH's project files

See all 415 nih grants

Papers492

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Decoding the shared genetic liability of lower respiratory tract infections via genomic structural equation modeling.BMC Pulm Med202642410578PubTator, text miningPubMed
Integrative Transcriptomic, Network, and Genomic Analysis of Peripheral Blood Mononuclear Cells Identifies Candidate Genes Associated with Dupilumab Clinical Response in Atopic Dermatitis Patients.Int J Mol Sci202642278672PubTator, text miningPubMed
Radiomics predicts poorly differentiated hepatocellular carcinoma and uncovers ribosomal-immune dysregulation mechanism.iScience202641732485PubTator, text miningPubMed
Processed Transcript Insertion as a Novel Germline Mutational Mechanism in BRCA1-Associated Hereditary Breast Cancer.Cancers (Basel)202541375073PubTator, text miningPubMed
Integrated single-cell and transcriptomic analysis of bone marrow-derived metastatic neuroblastoma reveals molecular mechanisms of metabolic reprogramming.Sci Rep202540764361PubTator, text miningPubMed
Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method.Front Genet202540357364PubTator, text miningPubMed
Identification of stable reference genes for relative quantification of long RNA expression in urinary extracellular vesicles.J Extracell Biol202438938675PubTator, text miningPubMed
hdWGCNA and Cellular Communication Identify Active NK Cell Subtypes in Alzheimer's Disease and Screen for Diagnostic Markers through Machine Learning.Curr Alzheimer Res202438808722PubTator, text miningPubMed
Significant Genes Associated with Mortality and Disease Progression in Grade II and III Glioma.Biomedicines202438672212PubTator, text miningPubMed
Distinct transcriptomic signatures define febrile malaria depending on initial infective states, asymptomatic or uninfected.BMC Infect Dis202438287287PubTator, text miningPubMed

1 to 10 of 492

See all 492 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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