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Gene · 6143

RPL19: ribosomal protein L19

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL19: ribosomal protein L19. Genes, record 6143. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6143

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Gene

Symbol
RPL19
HGNC
Name
ribosomal protein L19
HGNC
NCBI Gene ID
6143
NCBI Gene
HGNC ID
HGNC:10312
HGNC
Ensembl
ENSG00000108298
NCBI Gene
Aliases
DKFZp779D216, FLJ27452, L19, MGC71997, eL19
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P84098Large ribosomal subunit protein eL19196173Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462000P84098Espacenet
EP 4650780 A22025-11-19627P84098Espacenet
EP 4641201 A22025-10-29440P84098Espacenet
EP 4641202 A22025-10-294353P84098Espacenet
JP 2025517969 A2025-06-12440P84098Espacenet
JP 2025517970 A2025-06-12627P84098Espacenet
EP 4502182 A22025-02-0526P84098Espacenet
KR 1020250017231 A2025-02-044353P84098Espacenet
JP 2024054129 A2024-04-1626P84098Espacenet
US 11446398 B22022-09-2073991P84098Espacenet

1 to 10 of 40

See all 40 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants1,199

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL19 papersNewest fiscal year
P30CA016058Cancer Center Support Grant102025
P30CA008748Cancer Center Support Grant62025
P30ES023515Mount Sinai Center for Health and Environment Across the LifeSpan (HEALS)62025
P30CA016672Cancer Center Support Grant52025
P30CA042014Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center42025
P50CA136393Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancer42025
R35GM118103Recognition of Cellular Targets by single and double-stranded nucleic acids42025
T32HD049311Research Training Program in Pediatric Exposomics42025
P30CA013696Cancer Center Support Grant32025

1 to 10 of 1,199Source NIH's project files

See all 1,199 nih grants

Papers1,583

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genome-wide association study reveals putative genetic determinants of longitudinal immune responses to avian influenza and Newcastle disease in chickens.Genet Sel Evol202642638091PubTator, text miningPubMed
Single-Cell Analyses Reveal Dysregulation of Ribosomal Protein Genes During Hematopoietic Stem and Progenitor Cell Aging.Adv Biol (Weinh)202642596736PubTator, text miningPubMed
Evaluating Ribosomal Protein L19 mRNA as a Biomarker in Ulcerative Colitis: Implications for Severity Assessment.Mediators Inflamm202642033356PubTator, text miningPubMed
Upregulation of miR-4286 and miR-146a-5p in Metastatic Melanoma, Revealed by Multiplex Expression Analysis.Curr Issues Mol Biol202641899431PubTator, text miningPubMed
LncRNA Dlx4os drives malignant transformation and phenotype switching in melanoma.Epigenetics202641855479PubTator, text miningPubMed
The mouse gastric surface epithelial cell and its response to early Helicobacter pylori infection.Virulence202641824631PubTator, text miningPubMed
[Clinical and mechanistic study of Huoxue Tongbi Formula in intervening meridian blockage syndrome of steroid-induced osteonecrosis of femoral head by regulating coagulation-bone metabolism network].Zhongguo Zhong Yao Za Zhi202641814720PubTator, text miningPubMed
Nucleolus as a cornerstone linking proliferation and metabolism to cellular responses to stress: involvement of transcription factors MYC and p53.Front Mol Biosci202641777667PubTator, text miningPubMed
Manganese modulates hepatocellular carcinoma cytotoxicity and doxorubicin sensitivity in a dose dependent manner.Front Oncol202641768239PubTator, text miningPubMed
Study of the Cytotoxic and Wound Healing Activity of Polysaccharides from Bovistella utriformis.Molecules202641752430PubTator, text miningPubMed

1 to 10 of 1,583

See all 1,583 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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