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Gene · 6147

RPL23A: ribosomal protein L23a

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL23A: ribosomal protein L23a. Genes, record 6147. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6147

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Gene

Symbol
RPL23A
HGNC
Name
ribosomal protein L23a
HGNC
NCBI Gene ID
6147
NCBI Gene
HGNC ID
HGNC:10317
HGNC
Ensembl
ENSG00000198242
NCBI Gene
Aliases
L23A, MDA20, uL23
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62750Large ribosomal subunit protein uL23156181Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462013P62750Espacenet
EP 4650780 A22025-11-1912287P62750Espacenet
JP 2025517970 A2025-06-1212287P62750Espacenet
US 11446398 B22022-09-2074024P62750Espacenet
JP 2022524081 A2022-04-27176995P62750Espacenet
US 11078247 B22021-08-039754P62750Espacenet
WO 2020043864 A12020-03-052125P62750Espacenet
JP 2019054813 A2019-04-11242448P62750Espacenet
JP 2017197443 A2017-11-0260P62750Espacenet
JP 2017121241 A2017-07-13242448P62750Espacenet

1 to 10 of 31

See all 31 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants518

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL23A papersNewest fiscal year
P30CA008748Cancer Center Support Grant32025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA016086Cancer Center Support Grant22025
P30CA021765Cancer Center Support Grant (CCSG)22025
R01GM109215Functional Characterization of the Genetic and Environmental Determinants of Complex Traits22025
R01HL162574Psychosocial and Genetic Effects on Gene Expression and Asthma22025
K12GM068524San Diego IRACDA Scholars Program12025
P01AI063302The intersection of innate and adaptive immunity to intracellular pathogens12025

1 to 10 of 518Source NIH's project files

See all 518 nih grants

Papers641

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-cell transcriptomics combined with Mendelian randomization reveals the pivotal role of WDR83OS in clear cell renal cell carcinoma: An observational and bioinformatic study.Medicine (Baltimore)202642760660PubTator, text miningPubMed
FBXO5 regulates RPL23A to promote MDM2-mediated p53 degradation and facilitate malignant progression of breast cancer.Breast Cancer Res202642343437PubTator, text miningPubMed
xNNPCD identifies regulators of programmed cell death by integrating perturbation transcriptomes with cancer dependency profiles.bioRxiv202642182318PubTator, text miningPubMed
Diagnostic potential of circular RNAs in carotid atherosclerotic plaque vulnerability.Noncoding RNA Res202641809636PubTator, text miningPubMed
Manganese modulates hepatocellular carcinoma cytotoxicity and doxorubicin sensitivity in a dose dependent manner.Front Oncol202641768239PubTator, text miningPubMed
Organelles harbour pH gradients.Res Sq202641646419PubTator, text miningPubMed
Development of a split-toxin CRISPR screening platform to systematically identify regulators of human myoblast fusion.Nat Commun202641540035PubTator, text miningPubMed
Comprehensive whole genome sequence analysis unravels QTLs and genes under selection in Indian native riverine buffalo.Genome202641539658PubTator, text miningPubMed
Stable Cas9 expression regulates cell growth by facilitating mTORC2 activation.Nucleic Acids Res202541020501PubTator, text miningPubMed
Dual regulatory effects of gut microbiota and their metabolites in rheumatoid arthritis: balancing pathogenic and protective mechanisms.Front Immunol202540370449PubTator, text miningPubMed

1 to 10 of 641

See all 641 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6147

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