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Gene · 6184

RPN1: ribophorin I

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPN1: ribophorin I. Genes, record 6184. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6184

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Gene

Symbol
RPN1
HGNC
Name
ribophorin I
HGNC
NCBI Gene ID
6184
NCBI Gene
HGNC ID
HGNC:10381
HGNC
Ensembl
ENSG00000163902
NCBI Gene
Aliases
OST1, RBPH1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P04843Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 16076Ensembl, GeneID, HGNC

Source UniProt

Patents46

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-2619P04843Espacenet
JP 2026004568 A2026-01-1461945P04843Espacenet
EP 4650780 A22025-11-193701P04843Espacenet
JP 2025529142 A2025-09-043777P04843Espacenet
US 12371689 B22025-07-293777P04843Espacenet
JP 2025517970 A2025-06-123701P04843Espacenet
JP 2023554542 A2023-12-2746P04843Espacenet
US 11446398 B22022-09-2073882P04843Espacenet
US 11400116 B22022-08-022735P04843Espacenet
JP 2022524081 A2022-04-27176853P04843Espacenet

1 to 10 of 46

See all 46 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,059

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPN1 papersNewest fiscal year
ZIABC011490Maintaining cell health by targeted protein degradation92025
R01GM065334Solution structure and dynamics of polyubiquitin chains72025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control62025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA022453CANCER CENTER SUPPORT GRANT32025
P30CA046934University of Colorado Cancer Center Support Grant32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
P30EY010572Ophthalmology Core Facility32025

1 to 10 of 1,059Source NIH's project files

See all 1,059 nih grants

Papers1,418

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Congenital Disorders of Glycosylation (CDG): State of the Art in 2026.J Inherit Metab Dis202642813231PubTator, text miningPubMed
ITGBL1 and RPN1 Mark a Fibrotic NP Subpopulation with Coupled Integrin Signaling and N-Glycosylation Programs in IVDD.J Inflamm Res202642733874PubTator, text miningPubMed
PSKR: An LRR-RLK, enhances oxidative stress tolerance by modulating ROS-driven stomatal closure.Plant Sci202642710550PubTator, text miningPubMed
RPN1 at the crossroads of glycosylation, tumor immunity, and disulfidptosis.Front Pharmacol202642698633PubTator, text miningPubMed
Optimized post-GWAS analysis identifies therapeutic targets for essential thrombocythemia and polycythemia vera.Commun Med (Lond)202642277437PubTator, text miningPubMed
Integrative single-cell and spatial transcriptomics with machine learning identify a Luminal-inflam malignant program and reveal an RPN1-PERK UPR vulnerability in triple-negative breast cancer.Sci Rep202642270806PubTator, text miningPubMed
A homozygous nonsense variant in the oligosaccharyltransferase complex gene, RPN1, causes a congenital disorder of glycosylation.HGG Adv202641935956PubTator, text miningPubMed
Multi-omics identification of a programmed cell death-related signature and potential target P4HB for bladder cancer based on a 101-combination machine learning and experimental validation.Clin Exp Med202641925913PubTator, text miningPubMed
Structural dynamics of the midnolin-proteasome during ubiquitin-independent substrate turnover.Nat Commun202641896529PubTator, text miningPubMed
The oncogenic role of ecotropic viral integration site 1 in hematological malignancies: mechanisms of activation and leukemogenesis.Front Immunol202641777888PubTator, text miningPubMed

1 to 10 of 1,418

See all 1,418 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6184

GET https://conductscience.org/api/genes/v1/6184/patents?page=2