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Gene · 6191

RPS4X: ribosomal protein S4 X-linked

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPS4X: ribosomal protein S4 X-linked. Genes, record 6191. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6191

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Gene

Symbol
RPS4X
HGNC
Name
ribosomal protein S4 X-linked
HGNC
NCBI Gene ID
6191
NCBI Gene
HGNC ID
HGNC:10424
HGNC
Ensembl
ENSG00000198034
NCBI Gene
Aliases
CCG2, DXS306, FLJ40595, RPS4, S4, SCAR, SCR10, eS4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62701Small ribosomal subunit protein eS4, X isoform263198Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462151P62701Espacenet
EP 4650780 A22025-11-199348P62701Espacenet
EP 4641202 A22025-10-295593P62701Espacenet
JP 2025517970 A2025-06-129348P62701Espacenet
KR 1020250017231 A2025-02-045593P62701Espacenet
US 12116404 B22024-10-151P62701Espacenet
US 11446398 B22022-09-2074367P62701Espacenet
JP 2022524081 A2022-04-27177338P62701Espacenet
US 11078247 B22021-08-039803P62701Espacenet
WO 2020043864 A12020-03-052230P62701Espacenet

1 to 10 of 38

See all 38 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants1,149

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPS4X papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P40OD018537Bloomington Drosophila Stock Center at Indiana University42025
P30CA015704Cancer Center Support Grant32025
P30CA016086Cancer Center Support Grant32025
P30CA023108Cancer Center Support Grant32025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center32025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control32025
UL1TR001863Yale Clinical and Translational Science Award32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P20GM103449Vermont Biomedical Research Network-Vermont INBRE22025

1 to 10 of 1,149Source NIH's project files

See all 1,149 nih grants

Papers1,818

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Screening of Stable Reference Genes in Solea senegalensis Juveniles for Nervous Necrosis Virus (NNV) Vaccination Assays.Vet Sci202642655810PubTator, text miningPubMed
A retrospective study comparing the severe cutaneous adverse reactions in patients receiving triazole antifungal therapy and literature analysis.Med Mycol202642606393PubTator, text miningPubMed
Actin nucleation promoting factors drive Arp2/3 dependent endosomal microautophagy.bioRxiv202642465478PubTator, text miningPubMed
Inflammation, Scar, or Both? Interpreting Positron Emission Tomography Patterns in Cardiac Sarcoidosis.Circ J202642419928PubTator, text miningPubMed
Insights into the Phylogeny and Enigmatic Mitochondrial Biology of Eustigmatophyte Algae From Over 50 Newly Sequenced Organellar Genomes.Genome Biol Evol202642412603PubTator, text miningPubMed
A Hydrogen Sulfide-Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar-Suppressed Diabetic Wound Repair.Adv Sci (Weinh)202642363818PubTator, text miningPubMed
Analysis of B cell dynamic changes and pivotal drivers based on single-cell transcriptome of peripheral blood in sepsis.Blood Cells Mol Dis202642184475PubTator, text miningPubMed
Complete mitochondrial genome assembly and analysis of Astragalus (Papilionoideae: Fabaceae) species revealed its RNA editing and phylogenetic implications.BMC Plant Biol202642056870PubTator, text miningPubMed
Genetic variants in Rps4x cause intellectual disability with dysmorphic features, microcephaly, and autism.NPJ Genom Med202642031741PubTator, text miningPubMed
Case Report: Scar-Like Alterations of the Gastric Mucosa Observed Under Endoscopy in Collagenous Gastritis.Clin Case Rep202641970289PubTator, text miningPubMed

1 to 10 of 1,818

See all 1,818 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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