ConductScience.org, home

Gene · 6209

RPS15: ribosomal protein S15

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. RPS15: ribosomal protein S15. Genes, record 6209. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6209

On this page

Gene

Symbol
RPS15
HGNC
Name
ribosomal protein S15
HGNC
NCBI Gene ID
6209
NCBI Gene
HGNC ID
HGNC:10388
HGNC
Ensembl
ENSG00000115268
NCBI Gene
Aliases
MGC111130, RIG, S15, uS19
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62841Small ribosomal subunit protein uS19145196Ensembl, GeneID, HGNC

Source UniProt

Patents30

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462087P62841Espacenet
JP 2026004568 A2026-01-1462088P62841Espacenet
EP 4650780 A22025-11-1917752P62841Espacenet
JP 2025517970 A2025-06-1217752P62841Espacenet
US 11446398 B22022-09-2074224P62841Espacenet
JP 2022524081 A2022-04-27177195P62841Espacenet
KR 1020210045575 A2021-04-27119P62841Espacenet
KR 1020210045236 A2021-04-26119P62841Espacenet
JP 2019054813 A2019-04-11242522P62841Espacenet
JP 2019054813 A2019-04-11242523P62841Espacenet

1 to 10 of 30

See all 30 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants832

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPS15 papersNewest fiscal year
P30CA008748Cancer Center Support Grant52025
R35GM136323Dissecting the Mechanisms of Regulation and Quality Control in Ribosome Assembly and the Consequences of their Failure52025
P30CA016672Cancer Center Support Grant42025
P30CA015704Cancer Center Support Grant32025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P50CA196530Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer32025
R01CA155010Personal tumor neoantigens for immunity against chronic lymphocytic leukemia32025
R01DK108910Insulin and nutrient actions in the FGR fetal liver32025
ZIAAI000712Transcriptional control of herpes simplex virus lytic infection and latency-reactivation cycles32025
F31HL167530Leveraging CRISPR RNA-guided DNA Transposases for Gene Insertion at the CFTR Locus22025

1 to 10 of 832Source NIH's project files

See all 832 nih grants

Papers1,308

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Whole-transcriptome sequencing analysis to identify key non-coding RNAs in the pathogenesis of pulmonary tuberculosis.Public Health Action202642639598PubTator, text miningPubMed
HERC4 synergizes with USP16 to promote lung adenocarcinoma growth by augmenting protein translation via stabilizing RPS15.Oncogene202642527506PubTator, text miningPubMed
Phylogenomics, divergence time estimation, and biogeography of Iris species from Kazakhstan using plastome sequence analysis.Front Plant Sci202642389122PubTator, text miningPubMed
Characterisation of the chloroplast genome of Macrotyloma species: comparative analysis and phylogenomic insights.Sci Rep202642303652PubTator, text miningPubMed
Comparative chloroplast genomics of 22 species of Sida (Malvaceae) reveals structural conservation, adaptive evolution, and preliminary phylogenetic structure.BMC Plant Biol202642265602PubTator, text miningPubMed
A RiboCancer cell line panel reveals that CLL-associated Rps15 mutations translationally rewire transcription through codon-specific tRNA accommodation defects.Hemasphere202642255948PubTator, text miningPubMed
The RPS15-DDX21 complex drives prostate malignancy through transcriptional activation of SCD1.Oncogene202642098442PubTator, text miningPubMed
Stoichiometry-preserving and stochasticity-aware identification of m6A from direct RNA sequencing.Brief Bioinform202641921196PubTator, text miningPubMed
A single cell transcriptional profile of benign prostatic hyperplasia.Sci Rep202641832222PubTator, text miningPubMed
Proteomic mapping of Rosa damascena nanovesicles reveals plastid mitochondrial metabolic convergence and antimicrobial peptides.Plant Signal Behav202641803707PubTator, text miningPubMed

1 to 10 of 1,308

See all 1,308 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6209

GET https://conductscience.org/api/genes/v1/6209/patents?page=2