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Gene · 6217

RPS16: ribosomal protein S16

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPS16: ribosomal protein S16. Genes, record 6217. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6217

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Gene

Symbol
RPS16
HGNC
Name
ribosomal protein S16
HGNC
NCBI Gene ID
6217
NCBI Gene
HGNC ID
HGNC:10396
HGNC
Ensembl
ENSG00000105193
NCBI Gene
Aliases
S16, uS9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62249Small ribosomal subunit protein uS9146200Ensembl, GeneID, HGNC

Source UniProt

Patents36

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462091P62249Espacenet
EP 4650780 A22025-11-191343P62249Espacenet
EP 4641202 A22025-10-294452P62249Espacenet
JP 2025517970 A2025-06-121343P62249Espacenet
KR 1020250017231 A2025-02-044452P62249Espacenet
US 11446398 B22022-09-2074244P62249Espacenet
JP 2022524081 A2022-04-27177215P62249Espacenet
WO 2020043864 A12020-03-052219P62249Espacenet
JP 2019054813 A2019-04-11242526P62249Espacenet
US 9874572 B22018-01-23167P62249Espacenet

1 to 10 of 36

See all 36 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants707

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPS16 papersNewest fiscal year
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025
P30CA008748Cancer Center Support Grant32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P30AG066509University of Washington Alzheimer's Disease Research Center22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA016058Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202822025
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center22025
P30DK063491Diabetes Research Center (DRC)22025

1 to 10 of 707Source NIH's project files

See all 707 nih grants

Papers1,313

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The complete Chloroplast Genome of Dianthus Helenae, an Endemic Species with Medicinal Potential from the Nuratau Mountains, Uzbekistan.F1000Res202642732172PubTator, text miningPubMed
Rubus chingii chloroplast genome sequences: a comparative analysis with other Rubus L.chloroplast genomes.BMC Genomics202642410352PubTator, text miningPubMed
Phylogenomics, divergence time estimation, and biogeography of Iris species from Kazakhstan using plastome sequence analysis.Front Plant Sci202642389122PubTator, text miningPubMed
Comparative plastid genomics of Gastrochilus (Orchidaceae) with insights into molecular markers and phylogeny.BMC Genomics202642350970PubTator, text miningPubMed
Spontaneous plastome mutations in variegated plants occur predominantly in genes related to transcription and photosynthesis.Planta202642217055PubTator, text miningPubMed
Assessing the effect of parasite antigen genetic diversity on performance of Plasmodium vivax serological exposure markers for malaria: a multicentre observational diagnostic accuracy study.Lancet Microbe202642155491PubTator, text miningPubMed
Characterization and comparison of the complete chloroplast genome of Rubroshorea palembanica: an endemic and threatened dipterocarp.Planta202641951826PubTator, text miningPubMed
A new candidate tumor suppressor tRF-Ser inhibits gastric cancer progression by regulating the CNBP/HSPA8 axis.Cell Death Dis202641881984PubTator, text miningPubMed
Resolving Species Limits and Evolutionary Distinctiveness of the Libyan Endemic Arbutus pavarii (Ericaceae) Using Multilocus DNA Barcoding and Phylogenetic Analyses.Plants (Basel)202641754359PubTator, text miningPubMed
Plastome Evolution in Viburnum (Adoxaceae): Comparative Genomics Reveals Hypervariable Markers and Relaxed Selection on Protein Import Genes.Genes (Basel)202641751580PubTator, text miningPubMed

1 to 10 of 1,313

See all 1,313 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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