Gene · 6222
RPS18: ribosomal protein S18
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RPS18: ribosomal protein S18. Genes, record 6222. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6222
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P62269 | Small ribosomal subunit protein uS13 | 152 | 199 | Ensembl, GeneID, HGNC |
Source UniProt
Patents82
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 62094 | P62269 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 62095 | P62269 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 62096 | P62269 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 62098 | P62269 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 62099 | P62269 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 12566 | P62269 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 6278 | P62269 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 12566 | P62269 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 6278 | P62269 | Espacenet |
| JP 2024009871 A | 2024-01-23 | 74 | P62269 | Espacenet |
1 to 10 of 82
See all 82 patentsDrugs9
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ATALUREN | CHEMBL256997 | 80S Ribosome modulator | MODULATOR | ChEMBL |
| CITATUZUMAB BOGATOX | CHEMBL1743000 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| CYCLOHEXIMIDE | CHEMBL123292 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| DORLIMOMAB ARITOX | CHEMBL2109124 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| ELX-02 | CHEMBL4297744 | 80S Ribosome modulator | MODULATOR | ChEMBL |
| MT-3724 | CHEMBL4297789 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| TAPLITUMOMAB PAPTOX | CHEMBL2107890 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| TELIMOMAB ARITOX | CHEMBL2108790 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| ZOLIMOMAB ARITOX | CHEMBL2108785 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
Trials38
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07523581 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT05448755 | ELX-02 | PHASE2 | 2026-02-24 | ClinicalTrials.gov |
| NCT04336826 | ATALUREN | PHASE2 | 2024-04-01 | ClinicalTrials.gov |
| NCT04135495 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04126473 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04117880 | ATALUREN | PHASE2 | ClinicalTrials.gov | |
| NCT04069260 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04014530 | ATALUREN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT03796637 | ATALUREN | PHASE2 | 2022-04-05 | ClinicalTrials.gov |
| NCT03645395 | MT-3724 | PHASE2 | 2022-08-16 | ClinicalTrials.gov |
1 to 10 of 38
See all 38 trialsNIH grants1,052
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RPS18 papers | Newest fiscal year |
|---|---|---|---|
| P20GM103427 | Nebraska Research Network in Functional Genomics | 8 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 6 | 2025 |
| P30ES006694 | Southwest Environmental Health Sciences Center | 6 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA033572 | Cancer Center Support Grant | 3 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 3 | 2025 |
| P30DK065988 | UNC Cystic Fibrosis Research and Translation Core Center | 3 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 3 | 2025 |
| T32ES007091 | Training in Environmental Toxicology of Human Disease | 3 | 2025 |
1 to 10 of 1,052Source NIH's project files
See all 1,052 nih grantsPapers1,497
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The complete chloroplast genome of Indigofera argentea from Saudi Arabia: comparative genomic analysis within the genus Indigofera. | Front Plant Sci | 2026 | 42819347 | PubTator, text mining | PubMed |
| Characterisation of the chloroplast genome of Macrotyloma species: comparative analysis and phylogenomic insights. | Sci Rep | 2026 | 42303652 | PubTator, text mining | PubMed |
| A synergistic multi-omics approach: causal sepsis drivers identified in activated CD4+ T cells by single-cell RNA sequencing and Mendelian randomization. | Front Cell Infect Microbiol | 2026 | 42291321 | PubTator, text mining | PubMed |
| Selection of reference genes for normalization of quantitative real-time polymerase chain reaction analysis in foxglove aphid (Hemiptera: Aphididae). | J Econ Entomol | 2026 | 42161856 | PubTator, text mining | PubMed |
| MoSAIC: Codon Harmonization of Monte Carlo-Based Simulated Annealing for Linked Codons in Heterologous Protein Expression. | ACS Synth Biol | 2026 | 42130380 | PubTator, text mining | PubMed |
| 3-Aminoisoquinolines inhibit selectively phosphodiesterase 4B in KRAS-mutated colorectal cancer cell lines in-vitro and in-vivo. | Anticancer Drugs | 2026 | 41934673 | PubTator, text mining | PubMed |
| Association between omeprazole and memory impairment: Insights from NHANES data analysis and network pharmacology studies. | J Alzheimers Dis | 2026 | 41879275 | PubTator, text mining | PubMed |
| Monkeypox virus protein OPG188 antagonizes cGAS-STING antiviral signaling pathway to mediate immune evasion. | Proc Natl Acad Sci U S A | 2026 | 41849394 | PubTator, text mining | PubMed |
| Chloroplast genome comparison of Valeriana species with sequence variation, selective pressure, and divergence analysis. | PLoS One | 2026 | 41843567 | PubTator, text mining | PubMed |
| RSRC2 is a novel RNA-binding protein that safeguards mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1. | Nucleic Acids Res | 2026 | 41841495 | PubTator, text mining | PubMed |
1 to 10 of 1,497
See all 1,497 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6222
GET https://conductscience.org/api/genes/v1/6222/patents?page=2