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Gene · 6223

RPS19: ribosomal protein S19

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPS19: ribosomal protein S19. Genes, record 6223. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6223

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Gene

Symbol
RPS19
HGNC
Name
ribosomal protein S19
HGNC
NCBI Gene ID
6223
NCBI Gene
HGNC ID
HGNC:10402
HGNC
Ensembl
ENSG00000105372
NCBI Gene
Aliases
DBA, DBA1, LOH19CR1, S19, eS19
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P39019Small ribosomal subunit protein eS19145198Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462105P39019Espacenet
JP 2026004568 A2026-01-1462106P39019Espacenet
EP 4650780 A22025-11-1917845P39019Espacenet
EP 4641202 A22025-10-299165P39019Espacenet
JP 2025517970 A2025-06-1217845P39019Espacenet
KR 1020250017231 A2025-02-049165P39019Espacenet
US 11446398 B22022-09-2074273P39019Espacenet
US 11446398 B22022-09-2074274P39019Espacenet
JP 2022524081 A2022-04-27177244P39019Espacenet
JP 2022524081 A2022-04-27177245P39019Espacenet

1 to 10 of 35

See all 35 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants1,146

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPS19 papersNewest fiscal year
ZIACP010144Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes112025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis62025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias52025
P30CA008748Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA015704Cancer Center Support Grant32025
P30CA072720Cancer Center Support Grant32025
T32HL007574Pathophysiology of Human Blood Cells32025
UL1TR001863Yale Clinical and Translational Science Award32025

1 to 10 of 1,146Source NIH's project files

See all 1,146 nih grants

Papers1,720

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The complete chloroplast genome of Indigofera argentea from Saudi Arabia: comparative genomic analysis within the genus Indigofera.Front Plant Sci202642819347PubTator, text miningPubMed
Post-Transplant Cyclophosphamide-Based Related Haploidentical Transplantation for Adult Diamond-Blackfan Anemia: Long-Term Survival and Review.J Hematol202642730145PubTator, text miningPubMed
Chloroplast genome comparative analysis and phylogenetic relationships of 15 Syringa species (Oleaceae).Genet Mol Biol202642714267PubTator, text miningPubMed
Genetic variant profile in a cohort of inherited bone marrow failure patients from North india.Indian J Hematol Blood Transfus202642712617PubTator, text miningPubMed
[Clues for identifying Diamond-Blackfan anemia among infants with early severe anemia: Clinical and genetic analysis of 11 cases].Zhonghua Yi Xue Yi Chuan Xue Za Zhi202642711127PubTator, text miningPubMed
Generation of a human induced pluripotent stem cell panel from a family with a heterozygous RPS19 mutation including healthy wild-type, silent carrier and Diamond-Blackfan anemia individuals.Stem Cell Res202642710430PubTator, text miningPubMed
Insights into phylogenetic relationships of Veronica species (Plantaginaceae) based on comparative chloroplast genomics.Front Plant Sci202642682822PubTator, text miningPubMed
Results from the first clinical trial of bitopertin for steroid-relapsed/refractory Diamond-Blackfan anemia.Blood Red Cells Iron202642583025PubTator, text miningPubMed
Convergent nuclear proteostasis alterations across 40S ribosomal protein deficiencies.Nat Commun202642469271PubTator, text miningPubMed
Comparative plastome analysis and plastomic phylogeny of Moraceae with expanded species-level sampling.BMC Plant Biol202642458251PubTator, text miningPubMed

1 to 10 of 1,720

See all 1,720 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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