Gene · 6223
RPS19: ribosomal protein S19
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RPS19: ribosomal protein S19. Genes, record 6223. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6223
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P39019 | Small ribosomal subunit protein eS19 | 145 | 198 | Ensembl, GeneID, HGNC |
Source UniProt
Patents35
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 62105 | P39019 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 62106 | P39019 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 17845 | P39019 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 9165 | P39019 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17845 | P39019 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 9165 | P39019 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 74273 | P39019 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 74274 | P39019 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 177244 | P39019 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 177245 | P39019 | Espacenet |
1 to 10 of 35
See all 35 patentsDrugs9
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action | Source |
|---|---|---|---|---|
| ATALUREN | CHEMBL256997 | 80S Ribosome modulator | MODULATOR | ChEMBL |
| CITATUZUMAB BOGATOX | CHEMBL1743000 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| CYCLOHEXIMIDE | CHEMBL123292 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| DORLIMOMAB ARITOX | CHEMBL2109124 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| ELX-02 | CHEMBL4297744 | 80S Ribosome modulator | MODULATOR | ChEMBL |
| MT-3724 | CHEMBL4297789 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| TAPLITUMOMAB PAPTOX | CHEMBL2107890 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| TELIMOMAB ARITOX | CHEMBL2108790 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
| ZOLIMOMAB ARITOX | CHEMBL2108785 | 80S Ribosome inhibitor | INHIBITOR | ChEMBL |
Trials38
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07523581 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT05448755 | ELX-02 | PHASE2 | 2026-02-24 | ClinicalTrials.gov |
| NCT04336826 | ATALUREN | PHASE2 | 2024-04-01 | ClinicalTrials.gov |
| NCT04135495 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04126473 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04117880 | ATALUREN | PHASE2 | ClinicalTrials.gov | |
| NCT04069260 | ELX-02 | PHASE2 | ClinicalTrials.gov | |
| NCT04014530 | ATALUREN | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT03796637 | ATALUREN | PHASE2 | 2022-04-05 | ClinicalTrials.gov |
| NCT03645395 | MT-3724 | PHASE2 | 2022-08-16 | ClinicalTrials.gov |
1 to 10 of 38
See all 38 trialsNIH grants1,146
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RPS19 papers | Newest fiscal year |
|---|---|---|---|
| ZIACP010144 | Clinical Genetic Studies of Familial and Hereditary Cancer Syndromes | 11 | 2025 |
| R01DK103794 | Systematic Genetic Dissection of Human Erythropoiesis | 6 | 2025 |
| P01CA066996 | Development of Novel Therapeutic Strategies in Human Leukemias | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P30CA072720 | Cancer Center Support Grant | 3 | 2025 |
| T32HL007574 | Pathophysiology of Human Blood Cells | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
1 to 10 of 1,146Source NIH's project files
See all 1,146 nih grantsPapers1,720
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| The complete chloroplast genome of Indigofera argentea from Saudi Arabia: comparative genomic analysis within the genus Indigofera. | Front Plant Sci | 2026 | 42819347 | PubTator, text mining | PubMed |
| Post-Transplant Cyclophosphamide-Based Related Haploidentical Transplantation for Adult Diamond-Blackfan Anemia: Long-Term Survival and Review. | J Hematol | 2026 | 42730145 | PubTator, text mining | PubMed |
| Chloroplast genome comparative analysis and phylogenetic relationships of 15 Syringa species (Oleaceae). | Genet Mol Biol | 2026 | 42714267 | PubTator, text mining | PubMed |
| Genetic variant profile in a cohort of inherited bone marrow failure patients from North india. | Indian J Hematol Blood Transfus | 2026 | 42712617 | PubTator, text mining | PubMed |
| [Clues for identifying Diamond-Blackfan anemia among infants with early severe anemia: Clinical and genetic analysis of 11 cases]. | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | 2026 | 42711127 | PubTator, text mining | PubMed |
| Generation of a human induced pluripotent stem cell panel from a family with a heterozygous RPS19 mutation including healthy wild-type, silent carrier and Diamond-Blackfan anemia individuals. | Stem Cell Res | 2026 | 42710430 | PubTator, text mining | PubMed |
| Insights into phylogenetic relationships of Veronica species (Plantaginaceae) based on comparative chloroplast genomics. | Front Plant Sci | 2026 | 42682822 | PubTator, text mining | PubMed |
| Results from the first clinical trial of bitopertin for steroid-relapsed/refractory Diamond-Blackfan anemia. | Blood Red Cells Iron | 2026 | 42583025 | PubTator, text mining | PubMed |
| Convergent nuclear proteostasis alterations across 40S ribosomal protein deficiencies. | Nat Commun | 2026 | 42469271 | PubTator, text mining | PubMed |
| Comparative plastome analysis and plastomic phylogeny of Moraceae with expanded species-level sampling. | BMC Plant Biol | 2026 | 42458251 | PubTator, text mining | PubMed |
1 to 10 of 1,720
See all 1,720 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6223
GET https://conductscience.org/api/genes/v1/6223/patents?page=2