Gene · 623
BDKRB1: bradykinin receptor B1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BDKRB1: bradykinin receptor B1. Genes, record 623. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/623
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P46663 | B1 bradykinin receptor | 353 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 39083 | P46663 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 259 | P46663 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 573 | P46663 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 573 | P46663 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 259 | P46663 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9404 | P46663 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 9406 | P46663 | Espacenet |
| US 11732303 B2 | 2023-08-22 | 11 | P46663 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 9404 | P46663 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 9406 | P46663 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials4
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT01319487 | SAFOTIBANT | PHASE2 | ClinicalTrials.gov | |
| NCT01207973 | BI113823 | PHASE1 | ClinicalTrials.gov | |
| NCT00296569 | MK0686 | PHASE2 | ClinicalTrials.gov | |
| NCT00282763 | MK0686 | PHASE2 | ClinicalTrials.gov |
NIH grants929
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BDKRB1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30DK036836 | Diabetes Research Center | 4 | 2025 |
| R01HL049277 | Animal Models for Studying the Genetics of Complex Diseases | 4 | 2025 |
| T32GM007569 | Clinical Pharmacology Training Program | 4 | 2025 |
| ZIADA000493 | Functional and Pharmacological Significance of Receptor Heteromers in the CNS | 4 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 2 | 2025 |
| R01AI183620 | Role of the Hippo pathway in scleroderma pathogenesis | 2 | 2025 |
| R01NS106879 | Development and Characterization of Small Molecule Activators of Peptidase Neurolysin for Stroke Therapy | 2 | 2025 |
| T32AR007080 | Scientist Training in Rheumatology Research | 2 | 2025 |
| T32HL007227 | Pathophysiology of Myocardial Disease | 2 | 2025 |
1 to 10 of 929Source NIH's project files
See all 929 nih grantsPapers2,473
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Beta-Blockers for the Treatment of Arrhythmias: Which Drug for Which Arrhythmia? A State-of-the-Art Narrative Review. | Am J Cardiovasc Drugs | 2026 | 42766102 | PubTator, text mining | PubMed |
| G protein signaling capabilities at the bradykinin 2 receptor. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42547588 | PubTator, text mining | PubMed |
| Therapeutic Targeting of the Bradykinin B2 Receptor in Immunological and Vascular Diseases: Insights from Kinin Biology to Clinical Outcomes. | Clin Rev Allergy Immunol | 2026 | 42397484 | PubTator, text mining | PubMed |
Survival benefit analysis of beta-blockers in patients with sepsis-induced TnT-positive myocardial injury across different clinical subtypes of sepsis: A retrospective study based on the MIMIC-IV database. | Eur J Pharmacol | 2026 | 42248500 | PubTator, text mining | PubMed |
| G protein-coupled receptor autoantibody expression patterns in adults with decelerated biological aging mirror pediatric profiles. | BMC Immunol | 2026 | 42237231 | PubTator, text mining | PubMed |
| A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease. | Exp Mol Med | 2026 | 42236894 | PubTator, text mining | PubMed |
| Molecular mechanisms for subtype selectivity of kinin receptors' antagonists. | Nat Commun | 2026 | 42185275 | PubTator, text mining | PubMed |
| Kallikrein-8 contributes to kallikrein-kinin system dysregulation in Alzheimer's disease. | Exp Neurol | 2026 | 42140379 | PubTator, text mining | PubMed |
| BDKRB1 Links Copy Number-Defined Genomic Instability to Inflammatory and Immunosuppressive Tumor Ecosystems in Ovarian Cancer: An Integrative Multiomics Analysis. | Int J Genomics | 2026 | 42088621 | PubTator, text mining | PubMed |
| An Immunomodulating Peptide With Potential to Counteract Endometriosis. | Aust N Z J Obstet Gynaecol | 2026 | 41913689 | PubTator, text mining | PubMed |
1 to 10 of 2,473
See all 2,473 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/623
GET https://conductscience.org/api/genes/v1/623/patents?page=2