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Gene · 6239

RREB1: ras responsive element binding protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RREB1: ras responsive element binding protein 1. Genes, record 6239. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6239

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Gene

Symbol
RREB1
HGNC
Name
ras responsive element binding protein 1
HGNC
NCBI Gene ID
6239
NCBI Gene
HGNC ID
HGNC:10449
HGNC
Ensembl
ENSG00000124782
NCBI Gene
Aliases
FINB, HNT, LZ321, RREB-1, Zep-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q92766Ras-responsive element-binding protein 11,6870Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1461039Q92766Espacenet
JP 2026004568 A2026-01-1461040Q92766Espacenet
EP 4640849 A22025-10-29573Q92766Espacenet
EP 4641201 A22025-10-293898Q92766Espacenet
JP 2025147176 A2025-10-0615587Q92766Espacenet
JP 2025519096 A2025-06-24573Q92766Espacenet
JP 2025517969 A2025-06-123898Q92766Espacenet
JP 2025028160 A2025-02-2815587Q92766Espacenet
KR 1020250010750 A2025-01-2115587Q92766Espacenet
JP 2024109657 A2024-08-1415426Q92766Espacenet

1 to 10 of 35

See all 35 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,443

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRREB1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant242025
P30DK063491Diabetes Research Center (DRC)102025
P30CA016672Cancer Center Support Grant92025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION82025
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits82025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal82025
P30DK020572Michigan Diabetes Research Center (MDRC)72025
ZIAHG000024Genetic analysis of type II diabetes72025
UL1TR001881UCLA Clinical and Translational Science Institute62025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)52025

1 to 10 of 2,443Source NIH's project files

See all 2,443 nih grants

Papers2,585

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The bioinformatics approach to identifying pathogenic variants for colorectal cancer (CRC).J Genet Eng Biotechnol202642749394PubTator, text miningPubMed
ceRNA network of lncRNAs and mRNAs in OSF-to-OSCC progression: Diagnostic biomarkers and functional pathways.Comput Biol Chem202642551193PubTator, text miningPubMed
On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.Am J Dermatopathol202642358058PubTator, text miningPubMed
Avian Foxp3 acts as a switch for IL-10 by directly binding the T3G motif: revealing a novel epigenetic modulation paradigm.Cell Commun Signal202642351152PubTator, text miningPubMed
RBM15 transcription activated by EGR1 stimulates gastric cancer proliferation and metastasis by enhancing m6A modification of RREB1.Funct Integr Genomics202642213215PubTator, text miningPubMed
Spitz Melanocytoma With a Novel CPEB2::MAP3K2 Rearrangement: A Case Report.J Cutan Pathol202641924997PubTator, text miningPubMed
Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review).Int J Oncol202641860028PubTator, text miningPubMed
Proteomic Analysis of Cerebrospinal Fluid from Severe COVID-19 Patients Reveals Prognostic Biomarkers Associated with Disease Outcome.Proteomics Clin Appl202641830303PubTator, text miningPubMed
IFN signaling is associated with radiotherapy response in malignant peripheral nerve sheath tumors.J Clin Invest202641766654PubTator, text miningPubMed
Anaerobic riboflavin degradation by human gut Lachnospiraceae.bioRxiv202641757019PubTator, text miningPubMed

1 to 10 of 2,585

See all 2,585 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6239

GET https://conductscience.org/api/genes/v1/6239/patents?page=2