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BDNF: brain derived neurotrophic factor

1 protein, 604 patents, 0 drugs, 0 trials, 19,195 NIH grants and 53,263 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolBDNFHGNC
Namebrain derived neurotrophic factorHGNC
NCBI Gene ID627NCBI Gene
HGNC IDHGNC:1033HGNC
EnsemblENSG00000176697NCBI Gene
AliasesANON2, BULN2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P23560Neurotrophic factor BDNF precursor form2472Ensembl, GeneID, HGNCUniProt

Patents 604

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4762080 A12026-06-247P23560Espacenet
JP 2026067908 A2026-04-216P23560Espacenet
EP 4716540 A12026-04-0153P23560Espacenet
EP 4705273 A22026-03-11561P23560Espacenet
US 12560619 B22026-02-2442P23560Espacenet
JP 2026000906 A2026-01-0647P23560Espacenet
EP 4667578 A22025-12-24210P23560Espacenet
WO 2025245381 A12025-11-27153P23560Espacenet
EP 4650780 A22025-11-197329P23560Espacenet
EP 4637839 A12025-10-291P23560Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 19195

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001863Yale Clinical and Translational Science Award632,025NIH's project files
P30CA008748Cancer Center Support Grant592,025NIH's project files
ZIAMH002857Glutamatergic Modulators for Rapid and Sustained Antidepressant Effect552,025NIH's project files
ZIAMH002927Neurobiology and Target Validation of Novel Therapeutic Agents in Mood Disorders412,025NIH's project files
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)332,025NIH's project files
P30AG024827Pittsburgh Older Americans Independence Center312,025NIH's project files
P30CA016672Cancer Center Support Grant302,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)302,025NIH's project files
ZIAAA000301Integrative genetics of behavior with high throughput technologies302,025NIH's project files
P51OD011132Emory National Primate Research Center292,025NIH's project files

Papers 53263

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825082PubTator, text miningPubMed
42823991PubTator, text miningPubMed
42817934PubTator, text miningPubMed
42816980PubTator, text miningPubMed
42812344PubTator, text miningPubMed
42810733PubTator, text miningPubMed
42810402PubTator, text miningPubMed
42807812PubTator, text miningPubMed
42807488PubTator, text miningPubMed
42806147PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license