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S100A8: S100 calcium binding protein A8

1 protein, 217 patents, 0 drugs, 0 trials, 4,303 NIH grants and 8,375 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolS100A8HGNC
NameS100 calcium binding protein A8HGNC
NCBI Gene ID6279NCBI Gene
HGNC IDHGNC:10498HGNC
EnsemblENSG00000143546NCBI Gene
Aliases60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MRP-8, MRP8, NIF, P8, S100-A8NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05109Protein S100-A89313Ensembl, GeneID, HGNCUniProt

Patents 217

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462558P05109Espacenet
JP 2026004568 A2026-01-1462559P05109Espacenet
EP 4671272 A12025-12-31110P05109Espacenet
WO 2025259600 A22025-12-1899P05109Espacenet
EP 4641202 A22025-10-295438P05109Espacenet
JP 2025041681 A2025-03-2680P05109Espacenet
KR 1020250017231 A2025-02-045438P05109Espacenet
JP 2024131743 A2024-09-301P05109Espacenet
US 12097221 B22024-09-2416P05109Espacenet
EP 4368629 A12024-05-1569P05109Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4303

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant262,025NIH's project files
P30CA016672Cancer Center Support Grant222,025NIH's project files
R01GM118695Bioinorganic Explorations of Host-defense Proteins172,025NIH's project files
R01AI101171Host-mediated zinc sequestration during Acinetobacter baumannii infection152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases122,025NIH's project files
P30CA016087Cancer Center Support Grant112,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition112,025NIH's project files
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease102,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant92,025NIH's project files

Papers 8375

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824073PubTator, text miningPubMed
42820044PubTator, text miningPubMed
42818080PubTator, text miningPubMed
42812170PubTator, text miningPubMed
42807007PubTator, text miningPubMed
42806654PubTator, text miningPubMed
42794844PubTator, text miningPubMed
42770656PubTator, text miningPubMed
42760665PubTator, text miningPubMed
42737487PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license