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Gene · 6283

S100A12: S100 calcium binding protein A12

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. S100A12: S100 calcium binding protein A12. Genes, record 6283. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6283

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Gene

Symbol
S100A12
HGNC
Name
S100 calcium binding protein A12
HGNC
NCBI Gene ID
6283
NCBI Gene
HGNC ID
HGNC:10489
HGNC
Ensembl
ENSG00000163221
NCBI Gene
Aliases
CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P80511Protein S100-A12929Ensembl, GeneID, HGNC

Source UniProt

Patents78

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1462530P80511Espacenet
EP 4373841 A12024-05-2945P80511Espacenet
US 11754566 B22023-09-125P80511Espacenet
JP 2023518809 A2023-05-08117P80511Espacenet
US 11446398 B22022-09-2076255P80511Espacenet
JP 2022524081 A2022-04-27179226P80511Espacenet
US 11267854 B22022-03-081P80511Espacenet
US 11078247 B22021-08-039883P80511Espacenet
US 11047010 B22021-06-291771P80511Espacenet
US 11041865 B22021-06-221117P80511Espacenet

1 to 10 of 78

See all 78 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,713

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleS100A12 papersNewest fiscal year
P30DK058404Molecular and Cellular Basis for Digestive Diseases132025
P30AR070549Cincinnati Rheumatic Diseases Resource Center92025
R01GM118695Bioinorganic Explorations of Host-defense Proteins92025
P30CA016672Cancer Center Support Grant82025
P01CA116087H. pylori-induced Inflammation and Gastric Cancer72025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition72025
P30CA068485Cancer Center Support Grant62025
U24CA224319High-Dimensional Immune Monitoring of NCI-Supported Immunotherapy Trials62025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success62025
P01HL131481Macrophage Dysfunction in Atherosclerosis and Cardiometabolic Diseases52025

1 to 10 of 1,713Source NIH's project files

See all 1,713 nih grants

Papers3,572

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Novel cardiac biomarkers (serum S100A12 (Calgranulin C), FSTL1 (Follistatin-like 1), and osteocalcin) in patients with acute chest pain.J Med Biochem202642781349PubTator, text miningPubMed
Real-world insights into genomic reprogramming during CAR-T cell manufacturing in India.Front Immunol202642756106PubTator, text miningPubMed
Inflammatory Serum Olink Proteomics in Cancer-Related Pain Treated with Opioids: A Pilot Cross-Sectional and Longitudinal Study.J Proteome Res202642695881PubTator, text miningPubMed
Exploratory factor and network analysis of 43 inflammatory plasma biomarkers and cognitive performance in Black adults.J Alzheimers Dis202642684984PubTator, text miningPubMed
S100A8/A9 and S100A12 Proteins and Macrophage Polarization: Therapeutic Targets in Atherosclerosis.Biomolecules202642650783PubTator, text miningPubMed
Identification of Pyroptosis-Related Gene Signatures Associated with Predicted Immune-Cell Enrichment in Atrial Fibrillation.Genes (Basel)202642650051PubTator, text miningPubMed
The Roles of Four Neutrophil-Derived Proteins as Non-Invasive Biomarkers in the Assessment of Inflammatory Bowel Disease.J Inflamm Res202642638762PubTator, text miningPubMed
TRANCE is a unique marker of chronic pancreatitis in children.JCI Insight202642635043PubTator, text miningPubMed
Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock-Associated Immunosuppression: A Single-Cell Multi-Omics Study.MedComm (2020)202642609522PubTator, text miningPubMed
Apoptosis-related genes bridge inflammatory bowel disease and osteoporosis: A bioinformatic analysis.PLoS One202642585215PubTator, text miningPubMed

1 to 10 of 3,572

See all 3,572 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6283

GET https://conductscience.org/api/genes/v1/6283/patents?page=2