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S100B: S100 calcium binding protein B

1 protein, 105 patents, 0 drugs, 0 trials, 6,204 NIH grants and 14,655 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolS100BHGNC
NameS100 calcium binding protein BHGNC
NCBI Gene ID6285NCBI Gene
HGNC IDHGNC:10500HGNC
EnsemblENSG00000160307NCBI Gene
AliasesNEF, S100, S100-B, S100betaNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P04271Protein S100-B9215Ensembl, GeneID, HGNCUniProt

Patents 105

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-2475P04271Espacenet
JP 2026004568 A2026-01-1462561P04271Espacenet
JP 2026004568 A2026-01-1462562P04271Espacenet
EP 4650780 A22025-11-193474P04271Espacenet
EP 4641201 A22025-10-293060P04271Espacenet
EP 4641202 A22025-10-294707P04271Espacenet
JP 2025517969 A2025-06-123060P04271Espacenet
JP 2025517970 A2025-06-123474P04271Espacenet
JP 2025038035 A2025-03-184429P04271Espacenet
JP 2025032204 A2025-03-1135200P04271Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6204

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30AI036214San Diego Center for AIDS Research (SD CFAR)232,025NIH's project files
P30CA008748Cancer Center Support Grant202,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)192,025NIH's project files
P30CA068485Cancer Center Support Grant172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award162,025NIH's project files
P30CA016672Cancer Center Support Grant132,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition122,025NIH's project files
P30AG062715Wisconsin Alzheimer's Disease Research Center112,025NIH's project files
P30AI117970District of Columbia Center for AIDS Research102,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study92,025NIH's project files

Papers 14655

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824924PubTator, text miningPubMed
42822098PubTator, text miningPubMed
42813868PubTator, text miningPubMed
42808450PubTator, text miningPubMed
42807363PubTator, text miningPubMed
42801440PubTator, text miningPubMed
42800508PubTator, text miningPubMed
42799927PubTator, text miningPubMed
42797527PubTator, text miningPubMed
42795661PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license