Gene · 6303
SAT1: spermidine/spermine N1-acetyltransferase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SAT1: spermidine/spermine N1-acetyltransferase 1. Genes, record 6303. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6303
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P21673 | Diamine acetyltransferase 1 | 171 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents52
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 65257 | P21673 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10138 | P21673 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5729 | P21673 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10138 | P21673 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 35231 | P21673 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5729 | P21673 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 35231 | P21673 | Espacenet |
| JP 2024516160 A | 2024-04-12 | 6 | P21673 | Espacenet |
| KR 1020240001182 A | 2024-01-03 | 6 | P21673 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 35231 | P21673 | Espacenet |
1 to 10 of 52
See all 52 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,364
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SAT1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016056 | Roswell Park Cancer Center Support Grant | 17 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 13 | 2025 |
| P30CA023074 | University of Arizona Cancer Center - Cancer Center Support Grant | 10 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 6 | 2025 |
| P50HD052120 | Learning Disabilities Translational Science Collective: Building on the Florida LDRC | 6 | 2025 |
| P01CA116087 | H. pylori-induced Inflammation and Gastric Cancer | 5 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,364Source NIH's project files
See all 1,364 nih grantsPapers2,973
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated Single-Cell and Machine-Learning Analysis Identifies Antigen-Presenting Macrophage-Associated Genes in Pediatric Community-Acquired Pneumonia. | Curr Med Chem | 2026 | 42816984 | PubTator, text mining | PubMed |
| Integrative machine learning and transcriptomic analysis reveal a ferroptosis gene signature for pediatric Mycoplasma pneumoniae pneumonia. | Front Cell Dev Biol | 2026 | 42812455 | PubTator, text mining | PubMed |
| A biomarker-driven approach to targeting polyamine depletion in triple negative breast cancer. | Biomark Res | 2026 | 42811374 | PubTator, text mining | PubMed |
| High-Density Type I Collagen Promotes IFN-γ+ CD8+ T Cell Exhaustion via SAT1-ASS1-Mediated Glutamine Accumulation and Ferroptosis in Triple-Negative Breast Cancer. | Adv Sci (Weinh) | 2026 | 42801687 | PubTator, text mining | PubMed |
| Evolutionary and Spatiotemporal Dynamics of Foot-and-Mouth Disease Virus in Ethiopia (1957-2025): A Molecular Perspective on Serotype Persistence and Emergence. | Transbound Emerg Dis | 2026 | 42799644 | PubTator, text mining | PubMed |
| Unravelling Ferroptosis in Sepsis: A Comprehensive Integrative Transcriptomic Analysis Across Age and Disease Severity. | Bioinform Biol Insights | 2026 | 42756334 | PubTator, text mining | PubMed |
| SAT1 promotes prostate cancer progression and decreases enzalutamide sensitivity by enhancing spermine catabolism. | Hum Cell | 2026 | 42744967 | PubTator, text mining | PubMed |
| Polyethylene terephthalate micro-/nanoplastics suppress SAT1-dependent ferroptosis in triple-negative breast cancer. | Environ Int | 2026 | 42731238 | PubTator, text mining | PubMed |
| Divergent transcriptional programs and constrained metabolic states reveal selective metabolic dependencies in chemoresistant luminal breast cancer. | Cancer Drug Resist | 2026 | 42729982 | PubTator, text mining | PubMed |
| Polyamine Metabolism in Brain Health and Disease. | Neuropharmacol Ther | 2026 | 42631064 | PubTator, text mining | PubMed |
1 to 10 of 2,973
See all 2,973 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/6303
GET https://conductscience.org/api/genes/v1/6303/patents?page=2