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Gene · 6314

ATXN7: ataxin 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATXN7: ataxin 7. Genes, record 6314. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6314

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Gene

Symbol
ATXN7
HGNC
Name
ataxin 7
HGNC
NCBI Gene ID
6314
NCBI Gene
HGNC ID
HGNC:10560
HGNC
Ensembl
ENSG00000163635
NCBI Gene
Aliases
ADCAII, OPCA3, SCA7, SGF73
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15265Ataxin-78925Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-1979O15265Espacenet
JP 2026004568 A2026-01-1438057O15265Espacenet
JP 2026004568 A2026-01-1438060O15265Espacenet
EP 4640849 A22025-10-29475O15265Espacenet
EP 4641201 A22025-10-293260O15265Espacenet
JP 2025147176 A2025-10-0614778O15265Espacenet
JP 2025519096 A2025-06-24475O15265Espacenet
JP 2025517969 A2025-06-123260O15265Espacenet
JP 2025062604 A2025-04-146928O15265Espacenet
JP 2025062604 A2025-04-146930O15265Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants880

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATXN7 papersNewest fiscal year
R01EY014061SCA7 neurodegeneration: Molecular epigenetic basis and therapy282025
P30CA016672Cancer Center Support Grant102025
R01NS027699Molecular Studies of Spinocerebellar Ataxia Type 192025
P30EY001730Vision Research Core72025
R01NS086778MOLECULAR MECHANISMS OF NEUROPROTECTION IN POLYGLUTAMINE-DEPENDENT DEGENERATION62025
R01NS124854Targeting Cerebellar Endoplasmic Reticulum Calcium Handling in Essential Tremor62025
R01EY012543Vulnerable and Resilient Cells in Retinal Degeneration52025
R35GM118068Transcription regulation in chromatin52025
T32AG000266Training in Basic Research on Aging and Age-Related Disease52025
P40OD018537Bloomington Drosophila Stock Center at Indiana University42025

1 to 10 of 880Source NIH's project files

See all 880 nih grants

Papers1,627

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
MicroRNAs in polyglutamine diseases: Mechanistic insights, circulating biomarkers, and emerging microRNA-based therapeutic strategies.Neurobiol Dis202642716230PubTator, text miningPubMed
Convergent validity, responsiveness, and meaningful within-subject change of the PROM-Ataxia in spinocerebellar ataxias.J Neurol202642714627PubTator, text miningPubMed
Divergent somatic mutation patterns among human cerebellar neuron types.Neuron202642575091PubTator, text miningPubMed
Cerebellar ataxia in the Philippines: a scoping review of reported cases and practical approach.J Neural Transm (Vienna)202642573616PubTator, text miningPubMed
How Early Should I Refer My Patient? The Benefits of a Quick Ophthalmic Referral in Spinocerebellar Ataxias, a Case Series and Literature Review.Brain Sci202642512530PubTator, text miningPubMed
Nuclear Lamina Dysfunction and DNA Damage as Drivers of Premature Senescence in a Human Müller Glial Cell Model of Spinocerebellar Ataxia Type 7.Int J Mol Sci202642449987PubTator, text miningPubMed
Immune Activation and Glial Dysfunction in Spinocerebellar Ataxias: From Cerebellar Landscape to Disease-Driven Mechanisms and Immunomodulation.Cerebellum202642426383PubTator, text miningPubMed
Discovery of a mutation-containing circRNA in polyglutamine disease through systematic analysis of RNAs with CAG repeats.RNA Biol202642340810PubTator, text miningPubMed
Loss of astrocytic markers and impaired metabolic function in spinocerebellar ataxia type 7 patient-derived neural cultures.Neurobiol Dis202642264098PubTator, text miningPubMed
Correction: Key Modulators of the Stress Granule Response TIA1, TDP-43, and G3BP1 Are Altered by Polyglutamine-Expanded ATXN7.Mol Neurobiol202641995916PubTator, text miningPubMed

1 to 10 of 1,627

See all 1,627 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6314

GET https://conductscience.org/api/genes/v1/6314/patents?page=2