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Gene · 6317

SERPINB3: serpin family B member 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SERPINB3: serpin family B member 3. Genes, record 6317. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/6317

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Gene

Symbol
SERPINB3
HGNC
Name
serpin family B member 3
HGNC
NCBI Gene ID
6317
NCBI Gene
HGNC ID
HGNC:10569
HGNC
Ensembl
ENSG00000057149
NCBI Gene
Aliases
HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, SSCA1, T4-A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P29508Serpin B33903Ensembl, GeneID, HGNC

Source UniProt

Patents65

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463193P29508Espacenet
EP 4641201 A22025-10-292779P29508Espacenet
JP 2025517969 A2025-06-122779P29508Espacenet
US 11988676 B22024-05-2165P29508Espacenet
JP 2024038290 A2024-03-1965P29508Espacenet
JP 2023531521 A2023-07-2465P29508Espacenet
US 11446398 B22022-09-2078087P29508Espacenet
US 11400027 B22022-08-0216P29508Espacenet
JP 2022524081 A2022-04-27181058P29508Espacenet
US 11105806 B22021-08-3110P29508Espacenet

1 to 10 of 65

See all 65 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants975

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSERPINB3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant162025
P30CA008748Cancer Center Support Grant132025
U19AI070235Epithelial Genes in Allergic Inflammation62025
P30CA047904Cancer Center Support Grant52025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)42025
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease42025
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis42025
P30CA016086Cancer Center Support Grant32025
P30CA016087Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025

1 to 10 of 975Source NIH's project files

See all 975 nih grants

Papers2,569

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clade B serpins promote direct basal-to-goblet cell differentiation in airways of patients with chronic obstructive pulmonary disease.bioRxiv202642818353PubTator, text miningPubMed
Analytical standardization and inter-platform harmonization of immunoassay-based biomarkers in atopic dermatitis: Challenges and a roadmap for clinical laboratory implementation.Clin Chim Acta202642805450PubTator, text miningPubMed
Identification of key genes and metabolites in thyroid eye disease through integrated transcriptomic and metabolomic analysis.Front Endocrinol (Lausanne)202642769069PubTator, text miningPubMed
Conserved Epithelial Remodeling Programs Underlie Pediatric Juvenile Colorectal Polyps Associated with Allergic Sensitization.Int J Mol Sci202642737845PubTator, text miningPubMed
Human Wings Apart-Like Protein as a Serum Diagnostic Biomarker in Cervical Cancer: An Integrative Bioinformatics Analysis with Serum Validation.J Vis Exp202642631579PubTator, text miningPubMed
HPV16 E7-Associated SERPINB3 Suppression and MYC-Related Epithelial Plasticity in Head and Neck Squamous Cell Carcinoma.Cancers (Basel)202642588639PubTator, text miningPubMed
LAMC2+ Epithelial Cells Drive Bladder Cancer Progression and Predict Immunotherapy Response via SERPINB3/STAT3/CD44 Axis.Cancer Sci202642554210PubTator, text miningPubMed
Combined circulating tumor antigen model demonstrates additional prognostic value in first-line treatment of non-small cell lung cancer.J Immunother Cancer202642532630PubTator, text miningPubMed
Transcriptomic characterization of key psoriasis-associated genes based on single-cell RNA-seq and machine learning.PLoS One202642441578PubTator, text miningPubMed
HPV viral load predicts immune exhaustion and prognosis in cervical neoplasia.Front Immunol202642440646PubTator, text miningPubMed

1 to 10 of 2,569

See all 2,569 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/6317

GET https://conductscience.org/api/genes/v1/6317/patents?page=2